Protein Alignment Menl-2 and me1

DIOPT Version :10

• Sequence 1: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_002938500.1
• Gene: me1 / 100489590
• XenbaseID: XB-GENE-1013221
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 236/557 - (42%)
• Similarity: 350/557 - (62%)
• Gaps: 13/557 - (2%)

  Fly    27 YDDEMEQITRPDWHVVMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTD 91
            ||     ||| |.|:      |||:||:::||.:|||.||:|....|.|.|:...|.|:|.:..|
 Frog    34 YD-----ITR-DPHL------NKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRNYERQKCD 86

  Fly    92 IARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHI 156
            :.|:..|..:..|:.:|:|:.:..:||:.:|:|||||||.....|||.|::...|||:|||:|||
 Frog    87 LDRYILLMGLQDRNEKLFYKVLTSDIERFMPVVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHI 151

  Fly   157 RDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTD 221
            ..:|.:|.::.:||:.||||.|:|||||:|:..|||.:||:.||||.|.:.|...:||.||||||
 Frog   152 STVMKSWPEDNIKAVVVTDGERILGLGDLGSYGMGIPVGKLALYTACGGVQPQECLPVMLDVGTD 216

  Fly   222 NQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKY 286
            ||.||.||||:|.|..||:|.||||||||||::..:.:|.|..|.|||||..||.:.|..|:.||
 Frog   217 NQELLNDPLYIGLRHRRVRGKEYDELVDEFMKAVTERYGINCLIQFEDFANANAFRLLNMYRNKY 281

  Fly   287 CCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEAT 351
            |.||||||||.|..:|..:...|||..||.|...||.|||.||:|||:::.|.:|..|.|.:.|.
 Frog   282 CTFNDDIQGTAAVAVAGLLGALRITKNKLSDHTVLFQGAGEAAMGIADLIVMAMEKEGTPRDAAI 346

  Fly   352 KNIYLMDVNGILTPESPNPPEMGKIFIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKT 416
            |||:::|..|::.....:.....:.|....:.||.:..|:|.:||:||:|...:||.|.|:::|.
 Frog   347 KNIWMVDSKGLIVKGRASLNHEKERFAHPHKEMKSLEEVVKDIKPTVLIGVAAIGGAFTEQIIKD 411

  Fly   417 MAKNHERPAVFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVI-NGKRYRPAQANNCLTF 480
            ||..:.||.:|.|||||:.:||||||.:..|:||.:|.|||||.||.: :|:...|.|.||...|
 Frog   412 MASFNNRPIIFALSNPTSKAECTAEQCYRLTQGRGIFASGSPFDPVTLPDGRTLYPGQGNNAYVF 476

  Fly   481 PGIALAAITAKARYLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLID 545
            ||:||..:....|::.::||...:..:|:....:.|:||.|:||::....|:..:.|.:.:....
 Frog   477 PGVALGVVACGVRHISDDVFLTTAEIIAQQVSDKHLEEGRLYPPLQTIQEVSVKIAVKIVENAYK 541

  Fly   546 NDLSNVYPKPDDICEFVKRSLYKFDYRNSLPTTWDYP 582
            ::.::|:|:|::...||:..:|..||...:..::.:|
 Frog   542 DNSASVFPEPENKEAFVRSQMYSTDYDQFMVDSYSWP 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	235/546 (43%)
me1	XP_002938500.1	PLN03129	31..571	CDD:215594	235/548 (43%)