DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ste24c and ATSTE24

DIOPT Version :9

Sequence 1:	NP_001027433.1	Gene:	ste24c / 3772676	FlyBaseID:	FBgn0050462	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_567212.1	Gene:	ATSTE24 / 828209	AraportID:	AT4G01320	Length:	424	Species:	Arabidopsis thaliana

Alignment Length:	434	Identity:	127/434 - (29%)
Similarity:	222/434 - (51%)	Gaps:	29/434 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PIIVLVVLCLIVLVDRIWEMILTKRQQLVCLNAIMVPEELRGIIPPEIYHRARIYELHKTELQIW 76
            |.:..||..:||:.  |:|..|..| ||..|....:|:.|.|:|..|.:.::|.|.|.|:.....
plant     4 PFMETVVGFMIVMY--IFETYLDLR-QLTALKLPTLPKTLVGVISQEKFEKSRAYSLDKSYFHFV 65

  Fly    77 KYLIDLIITLCELILGFYPFLWSLSAKTLQKI---TSQEIWITLIFVFYLTIYICIRFLPVLIYD 138
            ...:.:::....|..|..|:.|.:|...|.::   ...||..||.|:..:..:..|..||..:|.
plant    66 HEFVTILMDSAILFFGILPWFWKMSGAVLPRLGLDPENEILHTLSFLAGVMTWSQITDLPFSLYS 130

  Fly   139 KCLLELRYGMSGKFPWYLYCCIGAMSILLSQLVLFPLAAAIVFSVKFIGYYFFLWFWLFWATFTL 203
            ..::|.|:|.:.:..| ::.........||.::..|:.|||:|.|:..|.|..::.|.|....:|
plant   131 TFVIESRHGFNKQTIW-MFIRDMIKGTFLSVILGPPIVAAIIFIVQKGGPYLAIYLWAFMFILSL 194

  Fly   204 LLVFFLPYCCIPCIGRQVVLPEGTALYMEVKRVCDVVGFPMKRVFII--KTRTMQYSNAYFYGSC 266
            :::...|....|...:...||:|. |..:::::...:.||:|::|::  .||: .:||||.||..
plant   195 VMMTIYPVLIAPLFNKFTPLPDGD-LREKIEKLASSLKFPLKKLFVVDGSTRS-SHSNAYMYGFF 257

  Fly   267 CLKRIVIFDTLLLNKGKEPNEIHPYEVGRGLTNIQVAGVVCHELGHWKHGHFYKATIIMKIHFFI 331
            ..||||::|| |:.:.|..:||              ..|:.|||||||..|...:.|.::|..|:
plant   258 KNKRIVLYDT-LIQQCKNEDEI--------------VAVIAHELGHWKLNHTTYSFIAVQILAFL 307

  Fly   332 TMGLFGLFFHSPQLYMAVGFEPGVMPIIVGFIIVLKFALTPYLTLANVLMLWNLRRFEYAADKFA 396
            ..|.:.|..:|..|:.:.||:  ..|:::| :|:.:..:.|...|.:..:....|.||:.||.||
plant   308 QFGGYTLVRNSTDLFRSFGFD--TQPVLIG-LIIFQHTVIPLQHLVSFGLNLVSRAFEFQADAFA 369

  Fly   397 HRMGYSIQLRMALVKIYADHMSFPVYDQCYARWHHTHPTILQRL 440
            .::||:..||.||||:..:::|....|..|:.:|::||.:::||
plant   370 VKLGYAKDLRPALVKLQEENLSAMNTDPLYSAYHYSHPPLVERL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ste24c	NP_001027433.1	Peptidase_M48_N	37..215	CDD:293100	45/180 (25%)
		HtpX	131..452	CDD:223575	94/312 (30%)
		Peptidase_M48	229..441	CDD:299867	69/214 (32%)
ATSTE24	NP_567212.1	M48A_Zmpste24p_like	8..417	CDD:320702	126/430 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I974
eggNOG	1	0.900	-	-		E1_COG0501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61664
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002450
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10120
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880