Protein Alignment ste24c and Zmpste24

DIOPT Version :9

• Sequence 1: NP_001027433.1
• Gene: ste24c / 3772676
• FlyBaseID: FBgn0050462
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: XP_006503082.1
• Gene: Zmpste24 / 230709
• MGIID: 1890508
• Length: 494
• Species: Mus musculus
• Alignment Length: 459
• Identity: 135/459 - (29%)
• Similarity: 233/459 - (50%)
• Gaps: 51/459 - (11%)

  Fly    28 IWEMILTKRQQLVCLNAIMVPEELRGIIPPEIYHRARIYELHKTELQIWKYLID----------- 81
            :||..|.:||:.:......||.||..|:..:.:.::|:|:|.|:....|..|..
Mouse    32 LWETFLAQRQRRIYKTTTRVPAELEQIMDSDTFEKSRLYQLDKSTFSFWSGLYSEVEGTDSSFPD 96

  Fly    82 --------LIITLCELILGFYPFLWSLSAKTLQKI---TSQEIWITLIFVFYLTIYICIRFLPVL 135
                    |..:|..|:.|..|:||.||.:.....   ...||..:|:|:...|::..:..||..
Mouse    97 HRRSESPILFHSLFILLFGGIPYLWRLSGQFCSSAGFGPEYEIIQSLVFLLLATLFSALTGLPWS 161

  Fly   136 IYDKCLLELRYGMSGK-FPWYLYCCIGAMSILLSQLVLFPLAAAIVFSVKFIGYYFFLWFWLFWA 199
            :|:..::|.::|.:.: ..:::...|  ...:::|.:|.|::|.:::.:|..|.|||::.|||..
Mouse   162 LYNTFVIEEKHGFNHQTLEFFMKDAI--KKFIVTQCILLPVSALLLYIIKIGGDYFFIYAWLFTL 224

  Fly   200 TFTLLLVFFLPYCCIPCIGRQVVLPEGTALYMEVKRVCDVVGFPMKRVFIIK-TRTMQYSNAYFY 263
            ..:|:||........|...:...|||| .|..|::.:...:.||:.:|:::: ::...:||||||
Mouse   225 VVSLVLVTIYADYIAPLFDKFTPLPEG-KLKQEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFY 288

  Fly   264 GSCCLKRIVIFDTLLLNKGKEPNEIHPYEVG----------------------RGLTNIQVAGVV 306
            |....||||:||| ||.:...||:.:..|.|                      :|..|.:|..|:
Mouse   289 GFFKNKRIVLFDT-LLEEYSVPNKDNQEESGMEARNEGEGDSEEVKAKVKNKKQGCKNEEVLAVL 352

  Fly   307 CHELGHWKHGHFYKATIIMKIHFFITMGLFGLFFHSPQLYMAVGFEPGVMPIIVGFIIVLKFALT 371
            .|||||||.||..|..||.:::.|:...||.:.....:|:.|.||... .|.::|.:|:.:|..:
Mouse   353 GHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRRELFAAFGFYDS-QPTLIGLLIIFQFIFS 416

  Fly   372 PYLTLANVLMLWNLRRFEYAADKFAHRMGYSIQLRMALVKIYADHMSFPVYDQCYARWHHTHPTI 436
            ||..:.:..:....||||:.||.||.::|.:..|..||:|:..|::.|||.|..::.||::||.:
Mouse   417 PYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSTWHYSHPPL 481

  Fly   437 LQRL 440
            |:||
Mouse   482 LERL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ste24c	NP_001027433.1	Peptidase_M48_N	37..215	CDD:293100	47/200 (24%)
		HtpX	131..452	CDD:223575	105/334 (31%)
		Peptidase_M48	229..441	CDD:299867	79/235 (34%)
Zmpste24	XP_006503082.1	M48A_Zmpste24p_like	22..490	CDD:320702	135/459 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61664
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002450
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10120
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.810