Protein Alignment ste24c and OMA1

DIOPT Version :10

• Sequence 1: NP_001027433.1
• Gene: ste24c / 3772676
• FlyBaseID: FBgn0050462
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_660286.1
• Gene: OMA1 / 115209
• HGNCID: 29661
• Length: 524
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 52/269 - (19%)
• Similarity: 87/269 - (32%)
• Gaps: 102/269 - (37%)

  Fly   222 VLPEGTALYMEVKRV------CD--------------VVGFPMKRVFIIKTRTMQYSNAYFYGSC 266
            :|.|..|.|:.||.|      |:              ||..|:...|::....|
Human   252 MLTEKDARYLAVKEVLCHLIECNKDVPGISQINWVIHVVDSPIINAFVLPNGQM----------- 305

  Fly   267 CLKRIVIFDTLLLNKGKEPNEIHPYEVGRGLTNIQVAGVVCHELGHWKHGH-FYKATIIMKIHFF 330
                 .:| |..||   ...:||           |::.::.||:.|...|| ..||.::..:.|
Human   306 -----FVF-TGFLN---SVTDIH-----------QLSFLLGHEIAHAVLGHAAEKAGMVHLLDF- 349

  Fly   331 ITMGLFGLFFHSPQLYMAVGFEPGVMPIIVGFIIVLKFALTPYLTLANVLMLW------------ 383
                 .|:.|                       :.:.:|:.|..:|| :|..|
Human   350 -----LGMIF-----------------------LTMIWAICPRDSLA-LLCQWIQSKLQEYMFNR 385

  Fly   384 -NLRRFEYAADKFAHRMGYSIQLRMALVKIYADHMSFPVYDQCYAR-----WHHTHPTILQRLAY 442
             ..|:.|..|||....:.......:....::...|.|  .|..:.:     |..|||:...|:.|
Human   386 PYSRKLEAEADKIGLLLAAKACADIRASSVFWQQMEF--VDSLHGQPKMPEWLSTHPSHGNRVEY 448

  Fly   443 QQKLDVKAM 451
            ..:|..:|:
Human   449 LDRLIPQAL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ste24c	NP_001027433.1	M48A_Zmpste24p_like	28..445	CDD:320702	50/261 (19%)
OMA1	NP_660286.1	Cardiolipin-binding. /evidence=ECO:0000250|UniProtKB:Q9D8H7	148..167
		Stress-sensor region. /evidence=ECO:0000250|UniProtKB:Q9D8H7	165..195
		M48C_Oma1_like	263..456	CDD:320690	47/255 (18%)