Protein Alignment bbx and Bbx

DIOPT Version :10

• Sequence 1: NP_001027087.1
• Gene: bbx / 3772670
• FlyBaseID: FBgn0024251
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_008766856.1
• Gene: Bbx / 303970
• RGDID: 1309769
• Length: 938
• Species: Rattus norvegicus
• Alignment Length: 667
• Identity: 165/667 - (24%)
• Similarity: 243/667 - (36%)
• Gaps: 241/667 - (36%)

  Fly   206 KLQDCSSDTDDEDDEEEDLDEEEDDEEEAEIQVQLPVQQEVTRIRREAAEEHVDVDVVTVPQQEQ 270
            ||.|.|.: ::||:||||:|           :|||
  Rat    35 KLLDFSEE-EEEDEEEEDID-----------KVQL------------------------------ 57

  Fly   271 DQYSHQVEPRQLQQD--ETADNTRPEHHARRPMNAFLIFCKRHRGIVKERYKTLENRAITKILGD 333
                  ||...|:||  ||.|:..||..|||||||||:||||||.:|::.:..|:||..||||.|
  Rat    58 ------VEADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILAD 116

  Fly   334 WWAALDEQEKHCFTDLAQQNKDAFFNANPNFKW-------YKLPAP---PLRTLATRPSNASAGL 388
            |||.||.:||..:||:|::.||||..|||.::|       .|.|.|   |.:.|...||::|
  Rat   117 WWAVLDPKEKQKYTDMAKEYKDAFMKANPGYRWCPTTNKPVKSPTPTVNPRKKLWAFPSDSS--- 178

  Fly   389 LIPSEDQPQQQVPTSLQVQWAERGEMPRAMLRPNYFKLADETQMGELSSLL-------------- 439
                     :.:||:.:   |:..|:|:.     .|.:||.||||.||.||
  Rat   179 ---------RDLPTAKK---AKTEEVPQL-----NFGMADPTQMGGLSMLLLAGEHALGTPEASS 226

  Fly   440 ---------QVQVQEKD--FALQQVLSETS---------------QFLSAHMPAGNTNGN----- 473
                     ..::::|.  |...::.|.||               ||...........|.
  Rat   227 GTCRPDISESPELRQKSPLFQFAEISSRTSHPDAPSKQCQASALFQFAEISSSTSQLGGTEPVKR 291

  Fly   474 -GNKRSLQ----------------------DNNSSNSSEEEAASGSSPNKKVKS----------- 504
             ||....|                      |::.....|.|........|..|:
  Rat   292 CGNSALFQLAEMCLASEGVKMEGTELTKSKDSDGGRIEEMEKGKEERDMKMEKTIETAFQAEAEF 356

  Fly   505 SRSCKGKIYQ-------ELVNSGQLAAIAKKSKARLPPAGNMGGNFVDIPLDAGPNTPPVSPPER 562
            .:|.||.|.:       |.:.|..:.||.                 |:.|.|:           |
  Rat   357 GKSAKGNIREPKDLRDIEQLQSDNVMAIK-----------------VEDPKDS-----------R 393

  Fly   563 QGSSPDSMQKHIRSVSESSSSGFFDLEEKIKELPA-------------LSLDAYLQRKRSTKKKK 614
            :.|..|....|....|.|:||...     |.::|:             :.....|.:....||||
  Rat   394 KESDDDQKYSHFPDFSYSASSKII-----ISDVPSRKDHMCHPHGIMIIEDPTALNKPEKIKKKK 453

  Fly   615 KFSGTKKQRNSNST----------SGASATSNVAAADAAAK---GAVPLSSEQHVRIKQQQ---- 662
            |.:...:..|..||          |.:...|.:...:|.||   ||..|......:::...
  Rat   454 KKNKLDRHGNDRSTPKKACKKRQSSESDIESVMYTIEAVAKGDWGADRLGETPRKKVRTSSSGKG 518

  Fly   663 --LQAVGSQRR-KARKESITRRDVSAIEQEVASILPLTINGSYYFNQSGAPKAVNAPVTSSSASP 724
              |.|...::: |::::.:::...|.|.:|  |..|..:|.|       |.|:|...|..|..:.
  Rat   519 GILDAKPPKKKVKSKEKKVSKEKCSDITKE--SRPPDFLNIS-------ASKSVPGEVPESMKAE 574

  Fly   725 PLSSNSSSSSSSLSSQA 741
            ||:....:...||..||
  Rat   575 PLTPTEDALPPSLPGQA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbx	NP_001027087.1	HMG-box_HBP2	298..366	CDD:438805	40/67 (60%)
Bbx	XP_008766856.1	HMG-box_HBP2	81..149	CDD:438805	40/67 (60%)
		DUF2028	191..322	CDD:430742	24/135 (18%)