Protein Alignment His1:CG33822 and H1-0

DIOPT Version :10

• Sequence 1: NP_001027314.1
• Gene: His1:CG33822 / 3772665
• FlyBaseID: FBgn0053822
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_005309.1
• Gene: H1-0 / 3005
• HGNCID: 4714
• Length: 194
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 89/252 - (35%)
• Similarity: 113/252 - (44%)
• Gaps: 71/252 - (28%)

  Fly     8 TSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIK 72
            ::::|.|.|                  .:||.:..:..||....|:.|:|:..|.|.|||..:|:
Human     5 STSAPAAKP------------------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQ 51

  Fly    73 KYITATYK----CDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKV 133
            |||.:.||    .|:|     ||..:|..|..|.|.||||.||||||:|:    |..:||
Human    52 KYIKSHYKVGENADSQ-----IKLSIKRLVTTGVLKQTKGVGASGSFRLA----KSDEPK----- 102

  Fly   134 LSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIK 198
                     |.||.||.....||.|.        .|||...||.|....|:|.||...||.   |
Human   103 ---------KSVAFKKTKKEIKKVAT--------PKKASKPKKAASKAPTKKPKATPVKKA---K 147

  Fly   199 SKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAK 255
            .|.|||..|  |.|||.|     ||||..::||||        |...|||||::|.:
Human   148 KKLAATPKK--AKKPKTV-----KAKPVKASKPKK--------AKPVKPKAKSSAKR 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
His1:CG33822	NP_001027314.1	H15	43..130	CDD:238028	38/90 (42%)
H1-0	NP_005309.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		7/41 (17%)
		Linker_histone	25..93	CDD:459846	32/72 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..194		59/150 (39%)