DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7215 and UBB

DIOPT Version :9

Sequence 1:	NP_001163644.1	Gene:	CG7215 / 3772662	FlyBaseID:	FBgn0038571	Length:	130	Species:	Drosophila melanogaster
Sequence 2:	NP_001268645.1	Gene:	UBB / 7314	HGNCID:	12463	Length:	229	Species:	Homo sapiens

Alignment Length:	151	Identity:	42/151 - (27%)
Similarity:	74/151 - (49%)	Gaps:	30/151 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQITIKVLKGKDCTIEVAPTSTILEVKHQIEAELQISATNQKLLLLGRPLNNEQTIASYPNIKEG 65
            |||.:|.|.||..|:||.|:.||..||.:|:.:..|....|:|:..|:.|.:.:|::.| ||::.
Human     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDY-NIQKE 64

  Fly    66 TKLNLVVIKPCLRDSILRGFRKHYSEPLA------ERMTNEFMADFERKINE------------- 111
            :.|:||     ||   |||..:.:.:.|.      |...::.:.:.:.||.:
Human    65 STLHLV-----LR---LRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIF 121

  Fly   112 --QSLDDLERLADSIVNRAAT 130
              :.|:|...|:|..:.:.:|
Human   122 AGKQLEDGRTLSDYNIQKEST 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7215	NP_001163644.1	UBQ	1..72	CDD:214563	27/70 (39%)
CG7215	NP_001163644.1	ubiquitin	6..72	CDD:278661	24/65 (37%)
UBB	NP_001268645.1	Ubl_ubiquitin	1..76	CDD:340501	32/83 (39%)
		Ubl_ubiquitin	77..152	CDD:340501	9/66 (14%)
		Ubl_ubiquitin	153..228	CDD:340501
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810