DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7215 and UBL4B

DIOPT Version :9

Sequence 1:	NP_001163644.1	Gene:	CG7215 / 3772662	FlyBaseID:	FBgn0038571	Length:	130	Species:	Drosophila melanogaster
Sequence 2:	NP_981957.1	Gene:	UBL4B / 164153	HGNCID:	32309	Length:	174	Species:	Homo sapiens

Alignment Length:	143	Identity:	30/143 - (20%)
Similarity:	69/143 - (48%)	Gaps:	23/143 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQITIKVLKGKDCTIEVAPTSTILEVKHQIEAELQISATNQKLLLLGRPLNNEQTIASY---PNI 62
            |.:|:|:|.|:.|:::|:...::..:|..:...|::....|.||..|:.|.:::.::.|   ||
Human     1 MFLTVKLLLGQRCSLKVSGQESVATLKRLVSRRLKVPEEQQHLLFRGQLLEDDKHLSDYCIGPN- 64

  Fly    63 KEGTKLNLVVIKPCLRDSILRGFR---------------KHYSEPLAERMTNEFMADFERKINEQ 112
               ..:| |:::|..:.::....:               ||:....|:.:......:.|.::.:.
Human    65 ---ASIN-VIMQPLEKMALKEAHQPQTQPLWHQLGLVLAKHFEPQDAKAVLQLLRQEHEERLQKI 125

  Fly   113 SLDDLERLADSIV 125
            ||:.||:||..::
Human   126 SLEHLEQLAQYLL 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7215	NP_001163644.1	UBQ	1..72	CDD:214563	18/73 (25%)
CG7215	NP_001163644.1	ubiquitin	6..72	CDD:278661	16/68 (24%)
UBL4B	NP_981957.1	UBQ	1..74	CDD:320785	19/77 (25%)
		FlhF	20..>154	CDD:332151	23/124 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..174
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5332
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48611
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005554
OrthoInspector	1	1.000	-	-		otm42102
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.920