DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33722 and Ubxn6

DIOPT Version :9

Sequence 1:	NP_001027152.1	Gene:	CG33722 / 3772658	FlyBaseID:	FBgn0064126	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_001366290.1	Gene:	Ubxn6 / 66530	MGIID:	1913780	Length:	442	Species:	Mus musculus

Alignment Length:	220	Identity:	66/220 - (30%)
Similarity:	91/220 - (41%)	Gaps:	36/220 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 KRTAPEEKASGSEPAKPLGESNQEQQPQPEPPKYDWGNGSGYLMNHPPEQKQAENEVEENPGRAP 280
            |.|.|.....|.|....||| :...|||             .|..|..:...||      |.||.
Mouse   225 KVTLPVPDQEGQEEFYVLGE-DARAQPQ-------------NLARHKQQLLDAE------PVRAT 269

  Fly   281 PVVKIIGPRQAVLFSLDESKKNANDLPDSFFDLTVNDLKMVLRDLKRTSSGDDDAPLLTAKLREL 345
            ...::...|.:.|.|..|       ||..||.||..::|...|  .||.:.:..:.|.|..:||.
Mouse   270 LDRQLRVFRPSALASHFE-------LPSDFFSLTAEEVKREQR--LRTEAVERLSSLRTKAMREK 325

  Fly   346 ERQKAMLAKLNQYKDCVLRIQFPDRFVLQGMFKPHEPLSKVEDFVREFLVQPGEQFHLFTIPPKK 410
            |.|:    :|.:|...::|::.||..:|||.|...|.||.:..||||.|......|.|.....:|
Mouse   326 EEQR----ELRKYTYALVRVRLPDGCLLQGTFYAREKLSALFRFVREALQNDWLPFELRASGGQK 386

  Fly   411 VLPSGETLL--ELNFVPNAIVHFGF 433
             |...|.|.  |...||:|::.|.:
Mouse   387 -LEENEALALNECGLVPSALLTFSW 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33722	NP_001027152.1	TUG-UBL1	8..71	CDD:288347
CG33722	NP_001027152.1	UBQ	360..429	CDD:294102	25/70 (36%)
Ubxn6	NP_001366290.1	Mediates interaction with LMAN1. /evidence=ECO:0000250\|UniProtKB:Q9BZV1	1..10
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..111
		VCP/p97-interacting motif (VIM). /evidence=ECO:0000250\|UniProtKB:Q9BZV1	51..63
		PUB_UBXD1	158..261	CDD:198418	13/49 (27%)
		UBX_UBXN6	336..409	CDD:340536	25/73 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900