DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mei-218 and rec

DIOPT Version :9

Sequence 1:	NP_001027068.1	Gene:	mei-218 / 3772646	FlyBaseID:	FBgn0002709	Length:	1186	Species:	Drosophila melanogaster
Sequence 2:	NP_001262615.1	Gene:	rec / 49241	FlyBaseID:	FBgn0003227	Length:	885	Species:	Drosophila melanogaster

Alignment Length:	192	Identity:	41/192 - (21%)
Similarity:	76/192 - (39%)	Gaps:	42/192 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   795 PLERHMIFRAPSQHGQEYPKPDL------NCVPSSIKKLHHLISSQYSDYSFVYALSAQISQDCV 853
            |..:.:..|..|...:|:.:.||      |..|:|.|.|             |.:::.::....:
  Fly   396 PYLKAVSIRDASSIKREFSERDLEAIVMINAEPNSFKLL-------------VQSIAPEVYGHEL 447

  Fly   854 PMDCFVYLKMILLASIVSIESDEVRAPISLCIIATDSLMANRLLNKVGQLAPRFLGPHEYG---- 914
            |       |...|.|::..:..|..| |::.::....:...::|....|:|.|  |.|..|
  Fly   448 P-------KAACLLSLLGGKGAETEA-INVLLVGDPGIGKTKILQSCAQIAER--GAHVSGKRGA 502

  Fly   915 -----LQPTFNALPTRFNWIVASPLLLAQQGVYYA-GDWNRLSKDQGCQLEKCIENGAVPVP 970
                 |..||.....|.  :.|..|::|..|.:.. .|.::|:..|...|: |:::..|.:|
  Fly   503 QSAQQLGVTFAGRNKRV--LQAGSLMMASGGGHCTLDDVDKLASKQAVLLQ-CLQSEEVNLP 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mei-218	NP_001027068.1	PTZ00112	122..>417	CDD:240274
mei-218	NP_001027068.1	MCM	<1023..1116	CDD:278895
rec	NP_001262615.1	RNR_PFL	<117..200	CDD:299130
		MCM	243..792	CDD:214631	41/192 (21%)
		P-loop_NTPase	468..606	CDD:304359	22/99 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11630
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100