Protein Alignment Shawn and SLC25A14

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 73/351 - (20%)
• Similarity: 130/351 - (37%)
• Gaps: 90/351 - (25%)

  Fly    50 AMVTACFMT-PLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTI 113
            |.:.|.|.| |:|:.|||||.|.|::                         .|..|.. ::.|..
Human    47 ASIVAEFGTFPVDLTKTRLQVQGQSI-------------------------DARFKEI-KYRGMF 85

  Fly   114 DAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHP 178
            .|..:|.:.||:.:|:||::|.|:.......|....|:..|..|.:      |..|.
Human    86 HALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVE------RLEDE-------- 136

  Fly   179 IPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQ-RMTHAEMFGTIRQVVQSQGVLGLWR----- 237
             ..|:.::.||...:::.|..:|.::::.:||:| .:....|.|:...:.|.:|..||||
Human   137 -TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRCLCSK 200

  Fly   238 --------------------------GLPPTILRDVPFSGIYWTCYEYLKSSF---GVVEPTFSF 273
                                      |:.||..|.....|:....|:..|...   |::..|...
Human   201 AVTGCVLWLMPVIPALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILT 265

  Fly   274 SFAAGAISGSVAATITTPFDVVKT---HEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGV 335
            .|.:....|...|..:.|.|||:|   :::...|...::          |.....:..:::..|.
Human   266 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLY----------KGTVDGILKMWKHEGF 320

  Fly   336 PAIFSGLGPRLFKVAPACAIMISSFE 361
            .|::.|..|...::.|...|...::|
Human   321 FALYKGFWPNWLRLGPWNIIFFITYE 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	29/109 (27%)
		Mito_carr	178..265	CDD:395101	23/121 (19%)
		Mito_carr	268..371	CDD:395101	18/97 (19%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	29/117 (25%)
		Mito_carr	134..254	CDD:395101	24/128 (19%)
		Mito_carr	262..351	CDD:395101	18/95 (19%)