Protein Alignment Shawn and HEM25

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_010164.1
• Gene: HEM25 / 851439
• SGDID: S000002277
• Length: 307
• Species: Saccharomyces cerevisiae
• Alignment Length: 354
• Identity: 83/354 - (23%)
• Similarity: 140/354 - (39%)
• Gaps: 76/354 - (21%)

  Fly    30 MTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCG 94
            ||:...:.|....:.....|.:.:|..:.|||::|||:|..::|.|       ...|.:
Yeast     1 MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKKATL-------WKNLKE------ 52

  Fly    95 PDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKAR--- 156
                              ||:.:::.|    |:|.|.|..::.|||..:.:..:.....|.|
Yeast    53 ------------------IDSPLQLWR----GTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAV 95

  Fly   157 ---FTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAE 218
               ..|.:..|.:     :..:|. :.....||.|...|.|......|:.:|:.:.:|....::.
Yeast    96 PSLTNDSNIVYNK-----SSSLPR-LTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSS 154

  Fly   219 MFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEP-------------- 269
            :...|..:...:|:.|.:||...|.|||.|::|:|...||..|....:|.|
Yeast   155 LKEAITHIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFTT 219

  Fly   270 --TFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRM 332
              :.:.:..:..:|.|:|.|:|.|||.:||..|:| ..||..|.|            ...||.:.
Yeast   220 YTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLE-PSKFTNSFN------------TFTSIVKN 271

  Fly   333 GGVPAIFSGLGPRLFKVAPACAIMISSFE 361
            ..|..:||||..||.:.|.:..|....:|
Yeast   272 ENVLKLFSGLSMRLARKAFSAGIAWGIYE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	24/125 (19%)
		Mito_carr	178..265	CDD:395101	23/86 (27%)
		Mito_carr	268..371	CDD:395101	29/110 (26%)
HEM25	NP_010164.1	Mito_carr	12..92	CDD:395101	23/114 (20%)
		Mito_carr	114..200	CDD:395101	23/86 (27%)
		Mito_carr	229..307	CDD:395101	28/85 (33%)