DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Shawn and SLC25A18

DIOPT Version :10

Sequence 1:NP_001027071.1 Gene:Shawn / 3772641 FlyBaseID:FBgn0031039 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_113669.1 Gene:SLC25A18 / 83733 HGNCID:10988 Length:315 Species:Homo sapiens


Alignment Length:343 Identity:80/343 - (23%)
Similarity:131/343 - (38%) Gaps:99/343 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 VTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAF 116
            ||..|  |:|:.|||||.|....:                                 :.|.||..
Human    23 VTCVF--PIDLAKTRLQNQHGKAM---------------------------------YKGMIDCL 52

  Fly   117 IKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPF 181
            :|.:|.||...::.|.:..|....|...|...|.:.|:....:         |.:..::.     
Human    53 MKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLME---------DGMQRNLK----- 103

  Fly   182 LVPLLAGVSGRILAVTCVSPVELIRTKMQ------------------------SQRMTHAEMFGT 222
             :.:|||....:..|....|:|:::.::|                        ....||.....|
Human   104 -MEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSAT 167

  Fly   223 I--RQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVE----PTFSFSFAAGAIS 281
            :  .:::::||:.||:|||..|:|||:|||.||:..:..| ::.|..|    .:|:.||.:|.::
Human   168 LIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANL-NNLGFNELAGKASFAHSFVSGCVA 231

  Fly   282 GSVAATITTPFDVVKTHEQ--------------IEFGEKFIFSDNPPKQVATKSVAMRLASIYRM 332
            ||:||...||.||:||..|              .:...|....:.|  ....|....|...|..:
Human   232 GSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGP--SAFMKGAGCRALVIAPL 294

  Fly   333 GGVP--AIFSGLGPRLFK 348
            .|:.  ..|.|:|.|:.|
Human   295 FGIAQGVYFIGIGERILK 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawnNP_001027071.1 Mito_carr 39..159 CDD:395101 24/106 (23%)
Mito_carr 178..265 CDD:395101 27/112 (24%)
Mito_carr 268..371 CDD:395101 27/101 (27%)
SLC25A18NP_113669.1 Mito_carr 4..97 CDD:395101 24/117 (21%)
Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 6..92 24/103 (23%)
Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 100..210 27/116 (23%)
Mito_carr 106..204 CDD:395101 26/97 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 141..160 0/18 (0%)
Mito_carr 217..302 CDD:395101 21/86 (24%)
Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 219..308 23/90 (26%)

Return to query results.
Submit another query.