DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shawn and SLC25A40

DIOPT Version :10

Sequence 1:NP_001027071.1 Gene:Shawn / 3772641 FlyBaseID:FBgn0031039 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_061331.2 Gene:SLC25A40 / 55972 HGNCID:29680 Length:338 Species:Homo sapiens


Alignment Length:351 Identity:159/351 - (45%)
Similarity:212/351 - (60%) Gaps:29/351 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 DPRFR------IRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHI 90
            ||..|      :.||||:.::||||::|:..:|||||:|.|||||...|...|||:|.||||||:
Human     2 DPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHL 66

  Fly    91 CPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKA 155
            |.| .:..|....|....|.||:|||.||.|.|||.||||||.|||:.|:|:|:|||..|:|..|
Human    67 CVC-EEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSA 130

  Fly   156 RFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMF 220
            .   :..|.......|            |::||:..|..|||.:||:|||||||||::.::.|:.
Human   131 L---LRSKLGENETCI------------PIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELH 180

  Fly   221 GTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLK----SSFGVVEPTFSFSFAAGAIS 281
            ..:.:.|...|.:.||||..||:|||||||.:||..||.||    ...|:.||||..:|.:||:|
Human   181 RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALS 245

  Fly   282 GSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRL 346
            ||.||..|.|||||||.:|.:.........:.|..::|..:   :.:|....|...:||||.|||
Human   246 GSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWII---MKNIVAKNGFSGLFSGLIPRL 307

  Fly   347 FKVAPACAIMISSFEYGKSFFYHYNI 372
            .|:|||||||||::|:||:||...|:
Human   308 IKIAPACAIMISTYEFGKAFFQKQNV 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawnNP_001027071.1 Mito_carr 39..159 CDD:395101 65/119 (55%)
Mito_carr 178..265 CDD:395101 40/90 (44%)
Mito_carr 268..371 CDD:395101 47/102 (46%)
SLC25A40NP_061331.2 Mito_carr 12..136 CDD:395101 65/127 (51%)
Solcar 1 13..131 64/118 (54%)
Solcar 2 139..223 41/95 (43%)
Mito_carr 145..228 CDD:395101 39/82 (48%)
Mito_carr 231..330 CDD:395101 47/101 (47%)
Solcar 3 233..327 44/96 (46%)

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