Protein Alignment Shawn and SLC25A36

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_047304396.1
• Gene: SLC25A36 / 55186
• HGNCID: 25554
• Length: 343
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 97/366 - (26%)
• Similarity: 148/366 - (40%)
• Gaps: 71/366 - (19%)

  Fly    18 AAASSQNPSKATMTDPRFRIRPLQQVAS--ACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCF 80
            ||...:.|..:.....|..:|.|   ||  || |..|.|....||:|:|||||:....|..::..
Human    19 AAGPGRTPQSSRRRGSRAALRSL---ASDFAC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQ 79

  Fly    81 LYCNGLMDHICPCGPDTPNPAAAKPAPRF--SGTIDAFIKISRTEGIGSLWSGLSPTLISALPST 143
            |                 |..|.....|.  .|.:.....|...||..||:.||.|.|:...||.
Human    80 L-----------------NTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSR 127

  Fly   144 IIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTK 208
            .|||.||...|.:..|:.     .||:..          |.:::.......|:|..:|:.||:|:
Human   128 AIYFAAYSNCKEKLNDVF-----DPDSTQ----------VHMISAAMAGFTAITATNPIWLIKTR 177

  Fly   209 MQSQRMTHAE----MFGTIRQVVQSQGVLGLWR-------GLPPTILRDVPFSGIYWTCYEYLKS 262
            :|.......|    .|..:|:|.|:.|:.|.:|       |:..|::..|.:..|.....||..:
Human   178 LQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTA 242

  Fly   263 SF------GVVEPT-FSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATK 320
            |.      .|.|.: |.....|.|.|.:.|.||..|.:||:|..: |.|.|:            :
Human   243 STMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLR-EEGTKY------------R 294

  Fly   321 SVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFE 361
            |....|:.:.:..|..:::.||...|.:..|..|||::::|
Human   295 SFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	39/123 (32%)
		Mito_carr	178..265	CDD:395101	23/103 (22%)
		Mito_carr	268..371	CDD:395101	26/95 (27%)
SLC25A36	XP_047304396.1	Mito_carr	40..145	CDD:395101	40/125 (32%)
		Mito_carr	146..240	CDD:395101	23/103 (22%)
		Mito_carr	258..343	CDD:395101	25/91 (27%)