DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Shawn and slc25a39

DIOPT Version :9

Sequence 1:	NP_001027071.1	Gene:	Shawn / 3772641	FlyBaseID:	FBgn0031039	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_012827167.1	Gene:	slc25a39 / 496786	XenbaseID:	XB-GENE-969813	Length:	412	Species:	Xenopus tropicalis

Alignment Length:	385	Identity:	171/385 - (44%)
Similarity:	226/385 - (58%)	Gaps:	58/385 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AAASSQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQAL---LSNK- 78
            |..||.:|...|         ||||:.::.|||::|:.|:|||||:|.|||||::.|   ||.|
Frog    59 AEESSSSPGGIT---------PLQQILASGTGALLTSLFVTPLDVVKIRLQAQRKPLSKVLSVKP 114

  Fly    79 -------------CFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWS 130
                         |||||||||||:..|...|......:....|:||:|||:||:|.||:.||||
Frog   115 LPWALPMRHPKWRCFLYCNGLMDHLFVCQHATACSTWYRAPTYFNGTLDAFVKITRHEGLTSLWS 179

  Fly   131 GLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDI----PHPIPFLVPLLAGVSG 191
            ||.|||:.|:|:|||||..|:|.:              |.:.:.:    .|     :||:||...
Frog   180 GLPPTLVMAVPATIIYFTCYDQLR--------------DFLCYGLGYHGSH-----IPLIAGALA 225

  Fly   192 RILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTC 256
            |:.|||.:||:|||||||||:::::.|:...:|..|...|.|.||:|..||:|||||||.:||..
Frog   226 RLGAVTVISPLELIRTKMQSRQLSYMELGVCLRSAVSQDGWLSLWKGWGPTVLRDVPFSALYWFN 290

  Fly   257 YEYLKSSF----GVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQV 317
            ||.:|...    ..||..|..||:|||:||:|||.:|.|||||||..|||.|...:....  ||.
Frog   291 YELVKKKMSNTKAAVESPFLVSFSAGAVSGAVAAVLTLPFDVVKTQRQIELGNLELGPSR--KQR 353

  Fly   318 ATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYN-IDQHN 376
            ::...|||  .|....|...:|:|..||:.||||||||||||:|:||:||...| |.|.|
Frog   354 SSTWGAMR--RIRAESGTRGLFAGFLPRVIKVAPACAIMISSYEFGKNFFQQQNKIKQQN 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:278578	66/136 (49%)
		Mito_carr	178..265	CDD:278578	41/90 (46%)
		Mito_carr	268..371	CDD:278578	52/102 (51%)
slc25a39	XP_012827167.1	Mito_carr	69..206	CDD:278578	68/159 (43%)
		Mito_carr	219..300	CDD:278578	40/80 (50%)
		Mito_carr	<326..401	CDD:278578	38/78 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5057
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2686
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		mtm9516
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2199
SonicParanoid	1	1.000	-	-		X1001
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.080