DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Shawn and GC2

DIOPT Version :9

Sequence 1:NP_001027071.1 Gene:Shawn / 3772641 FlyBaseID:FBgn0031039 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_731657.2 Gene:GC2 / 41449 FlyBaseID:FBgn0037970 Length:319 Species:Drosophila melanogaster


Alignment Length:368 Identity:85/368 - (23%)
Similarity:147/368 - (39%) Gaps:85/368 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 RFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTP 98
            :|.:.| :.:.....|.:..|| :.|||::|||||.|                     ..||:..
  Fly    17 KFNVFP-KIINGGVAGIIGVAC-VYPLDMVKTRLQNQ---------------------TIGPNGE 58

  Fly    99 NPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYK 163
            .        .::...|.|.|...:||...::.|.:..::...|...|...|.:.|:..       
  Fly    59 R--------MYTSIADCFRKTIASEGYFGMYRGSAVNIVLITPEKAIKLTANDFFRYH------- 108

  Fly   164 YTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQ-SQRMTHAE--------- 218
                   :|.| ...||.....|||....:..:...:|:||::.:|| :.|:..|:         
  Fly   109 -------LASD-DGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQMQDAGRVAAADRAAGREVKT 165

  Fly   219 --MFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYL-----KSSFGVVEPTFSFSFA 276
              ..|..:.:::.:|:.||::|:..|.:||:.||.:|:....::     :.|.|..|..|.:|..
  Fly   166 ITALGLTKTLLRERGIFGLYKGVGATGVRDITFSMVYFPLMAWINDQGPRKSDGSGEAVFYWSLI 230

  Fly   277 AGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSG 341
            ||.:||..:|.:.||||||||..|.:..:||            |.:...:....:..|:.|.|.|
  Fly   231 AGLLSGMTSAFMVTPFDVVKTRLQADGEKKF------------KGIMDCVNRTLKEEGISAFFKG 283

  Fly   342 LGPRLFKVAPACAIMISSFEYG-KSFFYHYNIDQHNRSNQATK 383
                     ..|.||:.:..:| ...||...:.:.....:.||
  Fly   284 ---------GLCRIMVLAPLFGIAQMFYFLGVGEKILGIERTK 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawnNP_001027071.1 Mito_carr 39..159 CDD:278578 25/119 (21%)
Mito_carr 178..265 CDD:278578 24/103 (23%)
Mito_carr 268..371 CDD:278578 30/103 (29%)
GC2NP_731657.2 PTZ00169 14..289 CDD:240302 78/338 (23%)
Mito_carr 16..106 CDD:278578 25/119 (21%)
Mito_carr 123..203 CDD:278578 20/79 (25%)
Mito_carr 228..302 CDD:278578 26/94 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45441492
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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