DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shawn and slc25a40

DIOPT Version :9

Sequence 1:	NP_001027071.1	Gene:	Shawn / 3772641	FlyBaseID:	FBgn0031039	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_989316.1	Gene:	slc25a40 / 394941	XenbaseID:	XB-GENE-1003942	Length:	341	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	160/356 - (44%)
Similarity:	224/356 - (62%)	Gaps:	28/356 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TDP---RFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICP 92
            |:|   ...|.|.||:.::..||::|:.|:|||||:|.|||||.:..:..|||:||||||||:|.
Frog     5 TEPVQEAINITPSQQMIASSMGALLTSFFVTPLDVVKIRLQAQSKPFIKGKCFVYCNGLMDHLCL 69

  Fly    93 CGPDTPNPAAAKPAP-RFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKAR 156
            |  ...|..|...|| .|.||.|||::|.|.|||.||||||.|||:.|:|:|:|||..|:|.:
Frog    70 C--TNGNGKAWYRAPGHFRGTTDAFVQIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLR-- 130

  Fly   157 FTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFG 221
                        |.:...:|.... :..|:||.:.|:.:.|.:||:||||||||.:.:::.|:..
Frog   131 ------------DILIRSMPERAE-IASLVAGATARLWSATLISPLELIRTKMQYRPLSYKELRQ 182

  Fly   222 TIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSS----FGVVEPTFSFSFAAGAISG 282
            .|:..|...|.|.||:|..||:|||||||.:||..||.:|.|    :..::|||:.||.|||:||
Frog   183 CIQSSVAKDGWLALWKGWGPTVLRDVPFSALYWHNYELVKQSLCQRYNTLQPTFAISFTAGAVSG 247

  Fly   283 SVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLF 347
            |:||.:|.|||||||..|:|.||..:|:.:..:..:|..:   :.:|....|...:|:||.|||.
Frog   248 SIAAIVTLPFDVVKTRRQVEVGELEMFTYSQKRSSSTWKL---MRAIVIENGFGGLFAGLIPRLI 309

  Fly   348 KVAPACAIMISSFEYGKSFFYHYNIDQHNRS 378
            |||||||||||::|:|||||...|.::..:|
Frog   310 KVAPACAIMISTYEFGKSFFRKLNNERQLKS 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:278578	63/120 (53%)
		Mito_carr	178..265	CDD:278578	38/90 (42%)
		Mito_carr	268..371	CDD:278578	52/102 (51%)
slc25a40	NP_989316.1	Mito_carr	14..135	CDD:365909	65/136 (48%)
		Solcar 1	14..132		64/133 (48%)
		Solcar 2	140..224		37/84 (44%)
		Mito_carr	143..225	CDD:365909	37/81 (46%)
		Mito_carr	234..331	CDD:365909	52/99 (53%)
		Solcar 3	234..328		49/96 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5057
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6040
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2686
OMA	1	1.010	-	-		QHG53824
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		mtm9516
Panther	1	1.100	-	-	LDO	PTHR45760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2199
SonicParanoid	1	1.000	-	-		X1001
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100