DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shawn and Slc25a40

DIOPT Version :9

Sequence 1:	NP_001027071.1	Gene:	Shawn / 3772641	FlyBaseID:	FBgn0031039	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001380639.1	Gene:	Slc25a40 / 296813	RGDID:	1308774	Length:	337	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	160/354 - (45%)
Similarity:	209/354 - (59%)	Gaps:	41/354 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDT 97
            |..::.||||:.::|.||:||:..:|||||:|.|||||.......|||||.||||||||.|..::
  Rat    10 PTIQVTPLQQMMASCAGAVVTSLMVTPLDVVKIRLQAQNNPFPKGKCFLYSNGLMDHICICEEES 74

  Fly    98 PNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARF-TDIH 161
            ......||. .|.||:|||:||.|.|||.||||||.|||:.|:|:|:|||..|||..... |.:.
  Rat    75 KKAWYKKPG-NFHGTLDAFLKIVRNEGIKSLWSGLPPTLVMAVPATVIYFTCYEQLSTFLKTKLG 138

  Fly   162 YKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQV 226
            ...||                :|::||:..|..|||.:||:|||||||||:..::.|::..:...
  Rat   139 ENETR----------------IPIVAGIVARFGAVTMISPLELIRTKMQSKTFSYKELYQIVSMK 187

  Fly   227 VQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLK----SSFGVVEPTFSFSFAAGAISGSVAAT 287
            |...|.:.||:|..||||||||||.:||..||.|:    ....:.|.||..:|.|||:|||.||.
  Rat   188 VSEDGWISLWKGWAPTILRDVPFSAMYWYNYENLRRWLCEKSDLYESTFMINFTAGALSGSFAAV 252

  Fly   288 ITTPFDVVK--------THEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGP 344
            .|.||||||        |||..:|.|        |..::|.|:   :.:|....|...:|:||.|
  Rat   253 ATLPFDVVKTQKQTQLWTHEYCKFPE--------PLDMSTWSI---MKNIVADRGFSGLFTGLIP 306

  Fly   345 RLFKVAPACAIMISSFEYGKSFFYHYNID 373
            ||.|:.|||||||||:|.||.||...|::
  Rat   307 RLVKIVPACAIMISSYELGKGFFQQQNVE 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:278578	66/120 (55%)
		Mito_carr	178..265	CDD:278578	39/90 (43%)
		Mito_carr	268..371	CDD:278578	50/110 (45%)
Slc25a40	NP_001380639.1	Mito_carr	13..137	CDD:395101	67/124 (54%)
		Solcar 1	14..132		66/118 (56%)
		Solcar 2	140..224		41/99 (41%)
		Mito_carr	146..229	CDD:395101	38/82 (46%)
		Mito_carr	232..330	CDD:395101	49/108 (45%)
		Solcar 3	234..328		47/104 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4669
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6040
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2735
OMA	1	1.010	-	-		QHG53824
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		mtm9100
orthoMCL	1	0.900	-	-		OOG6_101405
Panther	1	1.100	-	-	LDO	PTHR45760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1001
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.970