Protein Alignment Shawn and SLC25A41

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_775908.2
• Gene: SLC25A41 / 284427
• HGNCID: 28533
• Length: 370
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 57/244 - (23%)
• Similarity: 100/244 - (40%)
• Gaps: 67/244 - (27%)

  Fly    33 PRFRIRPLQQVASACTGAMVTACFMT---PLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCG 94
            |.|:.|.|       .|::..|...|   |::|:||||..::..
Human   184 PPFQERLL-------AGSLAVAISQTLINPMEVLKTRLTLRRTG--------------------- 220

  Fly    95 PDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTD 159
                         ::.|.:|...:|.:.||..:|:.|..|.::..:|........||..:..:.
Human   221 -------------QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWV- 271

  Fly   160 IHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVS----PVELIRTKMQSQ---RMTHA 217
                      ....|:..|..     |..:|...|:.||..    |:.|:||:||:|   ..::.
Human   272 ----------KSGRDMGDPSG-----LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNP 321

  Fly   218 EMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGV 266
            .|.|.:::::..||.|||:||:.||:|:.:|..||.:..||.:|.:.|:
Human   322 TMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTLGI 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	21/122 (17%)
		Mito_carr	178..265	CDD:395101	31/93 (33%)
		Mito_carr	268..371	CDD:395101
SLC25A41	NP_775908.2	PTZ00169	87..368	CDD:240302	56/240 (23%)
		Solcar 1. /evidence=ECO:0000255	90..176
		Solcar 2. /evidence=ECO:0000255	184..269		24/125 (19%)
		Solcar 3. /evidence=ECO:0000255	280..367		31/91 (34%)