Protein Alignment Shawn and SLC25A45

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_872362.4
• Gene: SLC25A45 / 283130
• HGNCID: 27442
• Length: 288
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 71/317 - (22%)
• Similarity: 121/317 - (38%)
• Gaps: 69/317 - (21%)

  Fly    59 PLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTE 123
            |.|.:|.|||.|                                    ..:.|.:|..:||.|.|
Human    22 PFDTVKVRLQTQ------------------------------------TTYRGIVDCMVKIYRHE 50

  Fly   124 GIGSLWSGLS-PTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLA 187
            .:...:.|:| |....|:.:::::.|............|.:...:|.:..|          ..||
Human    51 SLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMH----------IFLA 105

  Fly   188 GVSGRILAVTCVSPVELIRTKMQSQRMTHAE-------MFGTIR---QVVQSQGVLGLWRGLPPT 242
            |.:|..|...|::|.:||:.::|:|....|:       ..|.:.   .:.:.:|..||:||....
Human   106 GCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWAL 170

  Fly   243 ILRDVPFSGIYWTCYEYLKSSFGV--VEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGE 305
            .|||.|..|||:..||.|...:..  ..|:.:....||..:|..:....||.|::|:..|:
Human   171 TLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQM---- 231

  Fly   306 KFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEY 362
                 |...::|....:...::|| |..|:...|.|:.....:..|..|:...|:||
Human   232 -----DGLRRRVYQGMLDCMVSSI-RQEGLGVFFRGVTINSARAFPVNAVTFLSYEY 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	18/100 (18%)
		Mito_carr	178..265	CDD:395101	28/96 (29%)
		Mito_carr	268..371	CDD:395101	22/95 (23%)
SLC25A45	NP_872362.4	Solcar 1	1..83		18/96 (19%)
		Mito_carr	2..77	CDD:395101	17/90 (19%)
		Mito_carr	95..186	CDD:395101	27/100 (27%)
		Solcar 2	97..191		29/103 (28%)
		Mito_carr	197..288	CDD:395101	22/96 (23%)
		Solcar 3	199..286		22/94 (23%)