Protein Alignment Shawn and mfn-1

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001382726.1
• Gene: mfn-1 / 174752
• WormBaseID: WBGene00012204
• Length: 318
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 82/345 - (23%)
• Similarity: 139/345 - (40%)
• Gaps: 74/345 - (21%)

  Fly    39 PLQ--QVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDT--PN 99
            |:|  ..|.|..|| |..|.|.|.|.:|||:|:                    :||| |:|  |.
 Worm    18 PIQVHLTAGALAGA-VEHCVMFPFDSVKTRMQS--------------------LCPC-PETKCPT 60

  Fly   100 PAAAKPAPRFSGTIDAFIKISRTEGIGSLW----SGLSPTLISALPSTIIYFVAYEQFKARFTDI 160
            |            :.:.:.|.:.||    |    .|::.....::|:..:||..||:.|...|.
 Worm    61 P------------VHSLMSIVKREG----WLRPLRGVNAVAAGSMPAHALYFTVYEKMKGYLTG- 108

  Fly   161 HYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQ 225
              ......:|:|:.           .:||...::....::|.|:::.:||.....:.......|.
 Worm   109 --NSAGHSNTLAYG-----------ASGVVATLIHDAIMNPAEVVKQRMQMAFSPYGSSLECARC 160

  Fly   226 VVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEPTFSFS----FAAGAISGSVAA 286
            |...:||...:|.....:..:|||..|::..||:.:.   |:.|...:.    ..||.::|.:||
 Worm   161 VYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYEFWQH---VLNPEHKYDPKSHLIAGGLAGGLAA 222

  Fly   287 TITTPFDVVKT------HEQIEFGEKFIFSDNP-PKQVATKSVAMRLASIYRMGGVPAIFSGLGP 344
            .:|||.|.|||      ..:.:...:.||..|. ..:...:.::..:.:||...|:.....||..
 Worm   223 ALTTPMDCVKTVLNTQQAAEADPANRRIFLQNELQARYRYRGISDAVRTIYSQRGLSGFSCGLQA 287

  Fly   345 RLFKVAPACAIMISSFEYGK 364
            |:....||.|:..|.:|..|
 Worm   288 RVIFQVPATALSWSVYELFK 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	33/127 (26%)
		Mito_carr	178..265	CDD:395101	17/86 (20%)
		Mito_carr	268..371	CDD:395101	28/108 (26%)
mfn-1	NP_001382726.1	Mito_carr	16..110	CDD:395101	34/132 (26%)
		Mito_carr	112..199	CDD:395101	19/100 (19%)
		Mito_carr	<225..314	CDD:395101	22/83 (27%)