Protein Alignment Shawn and SLC25A25

DIOPT Version :10

• Sequence 1: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001317917.1
• Gene: SLC25A25 / 114789
• HGNCID: 20663
• Length: 515
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 77/326 - (23%)
• Similarity: 128/326 - (39%)
• Gaps: 65/326 - (19%)

  Fly    43 VASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAP 107
            ||....||:...| ..|||.:|..:|.  .|..||.
Human   237 VAGGGAGAVSRTC-TAPLDRLKVLMQV--HASRSNN----------------------------- 269

  Fly   108 RFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIA 172
              .|.:..|.::.|..|..|||.|....::...|.:.|.|:||||.| |......:..|     .
Human   270 --MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLR-----I 326

  Fly   173 HDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRM-THAEMFGTIRQVVQSQGVLGLW 236
            |:         .|:||.....:|.:.:.|:|:::|:|..::. .::.|....|:::..:||...:
Human   327 HE---------RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFY 382

  Fly   237 RGLPPTILRDVPFSGIYWTCYEYLKSSF------GVVEPTFSFSFAAGAISGSVAATITTPFDVV 295
            :|..|.:|..:|::||....||.||:::      ...:|......|.|.:|.:.....:.|..:|
Human   383 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 447

  Fly   296 KTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSF 360
            :|..|.:      .|.....:|...|:   ...|.|..|...::.||.|...||.||.:|....:
Human   448 RTRMQAQ------ASIEGAPEVTMSSL---FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVY 503

  Fly   361 E 361
            |
Human   504 E 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	30/115 (26%)
		Mito_carr	178..265	CDD:395101	22/93 (24%)
		Mito_carr	268..371	CDD:395101	23/94 (24%)
SLC25A25	NP_001317917.1	FRQ1	49..189	CDD:444056
		PTZ00169	237..491	CDD:240302	71/311 (23%)