DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gr59f and EEF1G

DIOPT Version :9

Sequence 1:	NP_788432.1	Gene:	Gr59f / 37726	FlyBaseID:	FBgn0041234	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	210	Identity:	42/210 - (20%)
Similarity:	68/210 - (32%)	Gaps:	75/210 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 NRTKRFIRLQLFLVG------------IFACLAIFFNIWTHKFVVYRSILSINSYVMPNIISSIS 199
            |||..|:|  .|..|            :|...||.:      :|....:..........::..:|
Human    44 NRTPEFLR--KFPAGKVPAFEGDDGFCVFESNAIAY------YVSNEELRGSTPEAAAQVVQWVS 100

  Fly   200 FAQYYLLLQGIAW---------RQRRLTEGLERELTHLHSPRISEVQKIRMHHANLID-FTKAVN 254
            ||...::.....|         ..::.||..:.|:..:               ..|:| :.|  .
Human   101 FADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRI---------------LGLLDAYLK--T 148

  Fly   255 RTFQYSILLLFVGCFLNFNLVLFLVYQGIENPSMADFTKWVCMLLWLAMHVGKVCSILHFNQSIQ 319
            |||       .||                |..::||.|. ||.||||...|.:.    .|.|:..
Human   149 RTF-------LVG----------------ERVTLADITV-VCTLLWLYKQVLEP----SFRQAFP 185

  Fly   320 NEHSTCLTLLSRVSY 334
            |.:...||.:::..:
Human   186 NTNRWFLTCINQPQF 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gr59f	NP_788432.1	7tm_7	61..388	CDD:303125	42/210 (20%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	11/45 (24%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/155 (20%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900