DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gdl and DGCR6L

DIOPT Version :9

Sequence 1:	NP_001027127.1	Gene:	gdl / 3772583	FlyBaseID:	FBgn0001099	Length:	194	Species:	Drosophila melanogaster
Sequence 2:	NP_150282.2	Gene:	DGCR6L / 85359	HGNCID:	18551	Length:	220	Species:	Homo sapiens

Alignment Length:	171	Identity:	65/171 - (38%)
Similarity:	102/171 - (59%)	Gaps:	13/171 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QRKIYFLVDQLRTYHSELPENLQTRISYDLLTELANCVLNDGIFVIVKALMELQHETERHLIKIR 94
            |.:.|.|:..|::...|||.:.|.|:||..|::||..:|:..:|.||:.|:|:||.||:.|...|
Human    18 QERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQR 82

  Fly    95 MQAENEYEIEVAEWRSKIKDPEEL--RHILGLMKIKHTKKL-----------HESDTKIIEILDQ 146
            ::.:||:.:.....|.|.::.::.  .|.|.:::....::|           ...|.|||..||:
Human    83 LRLQNEHRVLRQALRQKHQEAQQACRPHNLPVVQAAQQRELEAVEHRIREEQRAMDQKIILELDR 147

  Fly   147 KVNDQQSTLQKAGVPGFYVTENPKEIKIQMFLLDFILRLSR 187
            ||.||||||:||||.|||||.||:|:.:||.||:.|.:|.:
Human   148 KVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQ 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gdl	NP_001027127.1	DGCR6	29..194	CDD:284689	65/171 (38%)
DGCR6L	NP_150282.2	DGCR6	9..194	CDD:284689	65/171 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144819
Domainoid	1	1.000	109	1.000	Domainoid score	I6360
eggNOG	1	0.900	-	-		E1_KOG4810
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4891
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48814
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007511
OrthoInspector	1	1.000	-	-		otm41190
orthoMCL	1	0.900	-	-		OOG6_106863
Panther	1	1.100	-	-	O	PTHR13054
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5642
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.760