DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gdl and Dgcr6

DIOPT Version :9

Sequence 1:	NP_001027127.1	Gene:	gdl / 3772583	FlyBaseID:	FBgn0001099	Length:	194	Species:	Drosophila melanogaster
Sequence 2:	NP_001276742.1	Gene:	Dgcr6 / 13353	MGIID:	1202877	Length:	201	Species:	Mus musculus

Alignment Length:	181	Identity:	67/181 - (37%)
Similarity:	105/181 - (58%)	Gaps:	16/181 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QRKIYFLVDQLRTYHSELPENLQTRISYDLLTELANCVLNDGIFVIVKALMELQHETERHLIKIR 94
            |.:.|.|:..|::...|||.:.|.|:||..|::||..:|:..:|.||:.|:|:||.||:.|...|
Mouse    18 QERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQR 82

  Fly    95 MQAENEYEIEVAEWRSK-IKDPEELR-HILGLMKIKHTKKLHE--------------SDTKIIEI 143
            ::.:||:.:.....|.| ::..:..| |.|.:::....::|..              .|.||:..
Mouse    83 LRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELESWQAMEHRIREEQQAMDRKIVLE 147

  Fly   144 LDQKVNDQQSTLQKAGVPGFYVTENPKEIKIQMFLLDFILRLSRLKYEPGK 194
            ||:||.||||||:||||.|||||.||:|:.:||.||:.|.:|.:...:.||
Mouse   148 LDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRGCQVGK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gdl	NP_001027127.1	DGCR6	29..194	CDD:284689	65/179 (36%)
Dgcr6	NP_001276742.1	DGCR6	9..198	CDD:284689	65/179 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834930
Domainoid	1	1.000	111	1.000	Domainoid score	I6287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4152
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4867
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48814
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007511
OrthoInspector	1	1.000	-	-		oto93302
orthoMCL	1	0.900	-	-		OOG6_106863
Panther	1	1.100	-	-	LDO	PTHR13054
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10740
SonicParanoid	1	1.000	-	-		X5642
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.930