DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13430 and ST14

DIOPT Version :9

Sequence 1:	NP_001027441.1	Gene:	CG13430 / 3772580	FlyBaseID:	FBgn0034518	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	278	Identity:	97/278 - (34%)
Similarity:	139/278 - (50%)	Gaps:	35/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ICTSAAQNSTDVEQD--------------------GRIVGGWETHITFFPHQVSLQ-LGTRHACG 58
            :|.|......|.::|                    .|:|||.:.....:|.||||. ||..|.||
Human   578 LCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICG 642

  Fly    59 GTIISPNIILTAAHCVLE-----YSKPQYYVIRAGSSDWTK----GGSYIRVKKIIPHPEFHDPT 114
            .::||||.:::||||.::     ||.|..:....|..|.::    |....|:|:||.||.|:|.|
Human   643 ASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFT 707

  Fly   115 RMNNDIAIVQLQQPLVYSQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKRLRYTVVHL 179
             .:.|||:::|::|..||..:|||.|..:..:......::|:|||.|   |......|......:
Human   708 -FDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHT---QYGGTGALILQKGEI 768

  Fly   180 RDQNQCARNYFGAGTVTNTMFCAGTQAGGRDSCQGDSGGPLVT-SIDGRLKLYGIVSWGFGCANA 243
            |..||..........:|..|.|.|..:||.|||||||||||.: ..|||:...|:||||.|||..
Human   769 RVINQTTCENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQR 833

  Fly   244 MFPGIYTKVSAYDDWIAQ 261
            ..||:||::..:.|||.:
Human   834 NKPGVYTRLPLFRDWIKE 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	91/238 (38%)
CG13430	NP_001027441.1	Tryp_SPc	32..262	CDD:238113	92/241 (38%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060	4/23 (17%)
		Tryp_SPc	615..852	CDD:238113	92/241 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3952
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840