Protein Alignment CG13430 and PRSS2

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 104/270 - (38%)
• Similarity: 146/270 - (54%)
• Gaps: 33/270 - (12%)

  Fly    12 LWLICT-SAAQNSTDVEQDGRIVGGWETHITFFPHQVSLQLGTRHACGGTIISPNIILTAAHCV- 74
            |.||.| .||..:...:.|.:||||:.......|:||||..| .|.|||::||...:::|.||.
Human     3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSG-YHFCGGSLISEQWVVSAGHCYK 66

  Fly    75 -----------LEYSKPQYYVIRAG--SSDWTKGG-SYIRVKKIIPHPEFHDPTRMNNDIAIVQL 125
                       .||.:.|   :|.|  :.:..:|. .:|...|||.||:::..| ::|||.:::|
Human    67 SAINSKLSGRGCEYHRIQ---VRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRT-LDNDILLIKL 127

  Fly   126 QQPLVYSQDIRPISLATSKDIIMPTA--QLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARN 188
            ..|.|.:..:..|||.|:.    |.|  :..:||||:|..|.......|:.....:..|.:|..:
Human   128 SSPAVINSRVSAISLPTAP----PAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEAS 188

  Fly   189 YFGAGTVTNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWGFGCANAMFPGIYTKVS 253
            |  .|.:||.|||.|...||:||||||||||:|:  :|.|:  ||||||:|||....||:||||.
Human   189 Y--PGKITNNMFCVGFLEGGKDSCQGDSGGPVVS--NGELQ--GIVSWGYGCAQKNRPGVYTKVY 247

  Fly   254 AYDDWIAQTI 263
            .|.|||..||
Human   248 NYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	93/244 (38%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	95/246 (39%)