Protein Alignment CG13430 and PLAT

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 96/274 - (35%)
• Similarity: 134/274 - (48%)
• Gaps: 32/274 - (11%)

  Fly    13 WLICTSAAQNSTDVEQ----DGRIVGGWETHITFFPHQVSL------QLGTRHACGGTIISPNII 67
            |..|...:.::..:.|    ..||.||....|...|.|.::      ..|.|..|||.:||...|
Human   288 WEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWI 352

  Fly    68 LTAAHCVLEYSKPQYYVIRAGSSDWTKGG---SYIRVKKIIPHPEFHDPTRMNNDIAIVQLQQPL 129
            |:||||..|...|.:..:..|.:.....|   ....|:|.|.|.||.|.| .:||||::||:..
Human   353 LSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDT-YDNDIALLQLKSD- 415

  Fly   130 VYSQDIRPISLATSKDIIMPTAQLFVSGWGSTSIS------QMQP--EKRLRYTVVHLRDQNQCA 186
             .|:..:..|:.  :.:.:|.|.|.:..|....:|      .:.|  .:||:...|.|...::|.
Human   416 -SSRCAQESSVV--RTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCT 477

  Fly   187 RNYFGAGTVTNTMFCAG-TQAGG-----RDSCQGDSGGPLVTSIDGRLKLYGIVSWGFGCANAMF 245
            ..:....|||:.|.||| |::||     .|:||||||||||...|||:.|.||:|||.||.....
Human   478 SQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDV 542

  Fly   246 PGIYTKVSAYDDWI 259
            ||:||||:.|.|||
Human   543 PGVYTKVTNYLDWI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	91/250 (36%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	2/7 (29%)
		Tryp_SPc	313..559	CDD:238113	91/249 (37%)