Protein Alignment CG13430 and KLK12

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 82/254 - (32%)
• Similarity: 119/254 - (46%)
• Gaps: 31/254 - (12%)

  Fly     8 LAVALWLICTSAAQNSTDVEQDGRIVGGWETHITFFPHQVSLQLGTRHACGGTIISPNIILTAAH 72
            |::.|.|.....:|.:|.     :|..|.|......|.||.|..||...|||.:|....:|||||
Human     3 LSIFLLLCVLGLSQAATP-----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

  Fly    73 CVLEYSKPQYYVIRAGSS-----DWTKGGSYIRVKKI-IPHPEF-HDPTRMNNDIAIVQLQQPLV 130
            |    |..:|:| |.|..     |||:   .||.... :.||.: ...|...:|:.:::|:.|:.
Human    63 C----SGSRYWV-RLGEHSLSQLDWTE---QIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVR 119

  Fly   131 YSQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARNYFGAGTV 195
            .:..::|:.|  ..|......:..|||||.|:..:......|:...:.:.....|...|  .|.:
Human   120 VTSSVQPLPL--PNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVY--PGRI 180

  Fly   196 TNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWGF--GCANAMFPGIYTKV 252
            |:.|.||| ...|:|:||||||||||.   |.: |.|:||||.  .|.....||:||.:
Human   181 TSNMVCAG-GVPGQDACQGDSGGPLVC---GGV-LQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	77/231 (33%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	77/230 (33%)