Protein Alignment CG13430 and KLK2

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 94/271 - (34%)
• Similarity: 134/271 - (49%)
• Gaps: 28/271 - (10%)

  Fly     5 DFRLAVALWLICTSAAQNSTDVEQDGRIVGGWETHITFFPHQVSL-QLGTRHACGGTIISPNIIL 68
            |..|::||.:.||.|....     ..|||||||......|.||:: ..|..| |||.::.|..:|
Human     3 DLVLSIALSVGCTGAVPLI-----QSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVL 61

  Fly    69 TAAHCVLEYSKPQYYVIRAGSSDWTKGGSYIRVKKIIPHPEF------HDPTR----MNNDIAIV 123
            |||||:.:.|  |.::.|....:....|..:.|....|||.:      |...|    .::|:.::
Human    62 TAAHCLKKNS--QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124

  Fly   124 QLQQPLVYSQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARN 188
            :|.:|...:..::.:.|.|.:..:..|.  :.|||||....:....:.|:...:||...:.|||.
Human   125 RLSEPAKITDVVKVLGLPTQEPALGTTC--YASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA 187

  Fly   189 YFGAGTVTNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWG-FGCANAMFPGIYTKV 252
            |  :..||..|.|||...||:|:|.||||||||  .:|.|:  ||.||| ..||....|.:||||
Human   188 Y--SEKVTEFMLCAGLWTGGKDTCGGDSGGPLV--CNGVLQ--GITSWGPEPCALPEKPAVYTKV 246

  Fly   253 SAYDDWIAQTI 263
            ..|..||..||
Human   247 VHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	83/239 (35%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	84/241 (35%)