Protein Alignment CG13430 and KLK1

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 79/275 - (28%)
• Similarity: 130/275 - (47%)
• Gaps: 36/275 - (13%)

  Fly    12 LW--LICTSAAQNSTDVEQ--DGRIVGGWETHITFFPHQVSLQLGTRHACGGTIISPNIILTAAH 72
            :|  ::|.:.:...|....  ..|||||||......|.|.:|...:...|||.::....:|||||
Human     1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAH 65

  Fly    73 CVLEYSKPQYYVIRAGSSDWTKGGSYIRVKKIIPHPEFH-----DPTRM-----NNDIAIVQLQQ 127
            |:.:  ..|.::.|....|......::.|.:..|||.|:     :.||.     ::|:.:::|.:
Human    66 CISD--NYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTE 128

  Fly   128 PL-VYSQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEK-----RLRYTVVHLRDQNQCA 186
            |. ..:..::.:.|.|.:..:..|.  ..|||||     ::||.     .|:...:.:...::|.
Human   129 PADTITDAVKVVELPTEEPEVGSTC--LASGWGS-----IEPENFSFPDDLQCVDLKILPNDECK 186

  Fly   187 RNYFGAGTVTNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWGF-GCANAMFPGIYT 250
            :.:  ...||:.|.|.|...||:|:|.|||||||:  .||.|:  |:.|||: .|.....|.:..
Human   187 KAH--VQKVTDFMLCVGHLEGGKDTCVGDSGGPLM--CDGVLQ--GVTSWGYVPCGTPNKPSVAV 245

  Fly   251 KVSAYDDWIAQTIEE 265
            :|.:|..||..||.|
Human   246 RVLSYVKWIEDTIAE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	71/244 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	72/246 (29%)