DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13430 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001027441.1	Gene:	CG13430 / 3772580	FlyBaseID:	FBgn0034518	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	263	Identity:	95/263 - (36%)
Similarity:	138/263 - (52%)	Gaps:	19/263 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LICTSAAQNSTDV----EQDGRIVGGWETHITFFPHQVSL---QLGTRHACGGTIISPNIILTAA 71
            |||...:.:..:|    ..:.|||||.......:|.||||   :.| .|.|||::||...:||||
Zfish    14 LICVKGSLSQLNVCGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYG-GHFCGGSLISSEWVLTAA 77

  Fly    72 HCVLEYSKPQYYVIRAGSSDWTKGGSYI-----RVKKIIPHPEFHDPTRMNNDIAIVQLQQPLVY 131
            ||:...|:.. .|:..|..  |:.|..|     .|.|...|..::..|. :||||:::|...:.:
Zfish    78 HCLSGVSETT-LVVYLGRR--TQQGINIYETSRNVAKSFVHSSYNSNTN-DNDIALLRLSSAVTF 138

  Fly   132 SQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKR-LRYTVVHLRDQNQCARNYFGAGTV 195
            :..|||:.||....:.......:::|||........|... |:.|::.:...::| ....|:|||
Zfish   139 TNYIRPVCLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC-NALLGSGTV 202

  Fly   196 TNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWGFGCANAMFPGIYTKVSAYDDWIA 260
            ||.|.|||...||:|:||||||||:||.:.......||.|||:|||:...||:||:||.|..||:
Zfish   203 TNNMICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSWIS 267

  Fly   261 QTI 263
            ..|
Zfish   268 SKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	88/236 (37%)
CG13430	NP_001027441.1	Tryp_SPc	32..262	CDD:238113	89/238 (37%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	89/238 (37%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900