Protein Alignment CG13430 and HPN

DIOPT Version :10

• Sequence 1: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 95/261 - (36%)
• Similarity: 137/261 - (52%)
• Gaps: 15/261 - (5%)

  Fly    15 ICTSAAQNSTDVEQDGRIVGGWETHITFFPHQVSLQLGTRHACGGTIISPNIILTAAHCVLEYSK 79
            ||....:....|:   |||||.:|.:..:|.||||:....|.|||:::|.:.:||||||..|.::
Human   149 ICQDCGRRKLPVD---RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNR 210

  Fly    80 --PQYYVIRAGSSDWTKGGSYIRVKKIIPHP---EFHDPT--RMNNDIAIVQLQQPLVYSQDIRP 137
              .::.|.....:..:..|..:.|:.::.|.   .|.||.  ..:||||:|.|..||..::.|:|
Human   211 VLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 275

  Fly   138 ISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARNYFGAGTVTNTMFCA 202
            :.|..:...::......|:|||:|.....|... |:...|.:...:.|....|....:...||||
Human   276 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCA 339

  Fly   203 GTQAGGRDSCQGDSGGPLV----TSIDGRLKLYGIVSWGFGCANAMFPGIYTKVSAYDDWIAQTI 263
            |...||.|:||||||||.|    .|...|.:|.||||||.|||.|..||:|||||.:.:||.|.|
Human   340 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAI 404

  Fly   264 E 264
            :
Human   405 K 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	88/238 (37%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	2/9 (22%)
		Tryp_SPc	163..400	CDD:238113	87/237 (37%)