DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsp22 and Hspb8

DIOPT Version :9

Sequence 1:	NP_001027114.1	Gene:	Hsp22 / 3772576	FlyBaseID:	FBgn0001223	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_109629.1	Gene:	Hspb8 / 80888	MGIID:	2135756	Length:	196	Species:	Mus musculus

Alignment Length:	159	Identity:	47/159 - (29%)
Similarity:	71/159 - (44%)	Gaps:	28/159 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RSLPMFWRMAEEMARMPRLSSPFHAFFHEP-PVWSVALPR---NWQQIARWQEQEFAPPAT---- 58
            |..|:..|:.::...|    .||......| |.|  ||||   .|....|.......||||
Mouse    22 RDSPLSSRLLDDGFGM----DPFPDDLTAPWPEW--ALPRLSSAWPGTLRSGMVPRGPPATARFG 80

  Fly    59 VNKDG----------YKLTLDVKDY--SELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRF 111
            |..:|          :|:.::|..:  .||.||..| ..|.|.||.|::: ::||..|::|.::.
Mouse    81 VPAEGRSPPPFPGEPWKVCVNVHSFKPEELMVKTKD-GYVEVSGKHEEKQ-QEGGIVSKNFTKKI 143

  Fly   112 VLPEGYEADKVTSTLSSDGVLTISVPNPP 140
            .||...:...|.::||.:|:|.|..|..|
Mouse   144 QLPAEVDPATVFASLSPEGLLIIEAPQVP 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	IbpA	17..154	CDD:223149	44/144 (31%)
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	25/88 (28%)
Hspb8	NP_109629.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		2/5 (40%)
		ACD_HspB8_like	80..170	CDD:107235	26/91 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..196
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700