DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp22 and hspb6

DIOPT Version :9

Sequence 1:	NP_001027114.1	Gene:	Hsp22 / 3772576	FlyBaseID:	FBgn0001223	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_001094428.1	Gene:	hspb6 / 792610	ZFINID:	ZDB-GENE-080214-7	Length:	142	Species:	Danio rerio

Alignment Length:	145	Identity:	45/145 - (31%)
Similarity:	68/145 - (46%)	Gaps:	30/145 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FHEPP-------VWSVALPRNWQQI------ARWQEQEFAPP---------ATVNKDGYKLTLDV 70
            |..||       .|...||..:.::      ..|...||..|         .|.:.:|:.:.:||
Zfish     3 FDLPPSVPVSGIPWERVLPPLFPRLNGTIGPYSWTPTEFLIPVTEQTGASKVTCDHNGFTVEVDV 67

  Fly    71 KDYS--ELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLT 133
            |.:|  ||.|||..:.|| ||||.||:: :..|..:|.|.||:.:|.|.....:.|.:|.:|:|.
Zfish    68 KHFSPEELLVKVSGDYVV-VEGKHEQKK-DGSGLVTRQFNRRYRIPNGVNIMALESAMSPEGMLV 130

  Fly   134 ISVPNPPGVQETLKE 148
            ||.|    :.:|:.|
Zfish   131 ISAP----LTQTIPE 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	IbpA	17..154	CDD:223149	45/145 (31%)
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	31/78 (40%)
hspb6	NP_001094428.1	metazoan_ACD	53..135	CDD:107247	33/87 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870