DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp22 and hspb8

DIOPT Version :9

Sequence 1:	NP_001027114.1	Gene:	Hsp22 / 3772576	FlyBaseID:	FBgn0001223	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_001005658.1	Gene:	hspb8 / 448147	XenbaseID:	XB-GENE-945643	Length:	202	Species:	Xenopus tropicalis

Alignment Length:	148	Identity:	44/148 - (29%)
Similarity:	68/148 - (45%)	Gaps:	27/148 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPMFWRMAEEMARMPRLSSPFHAFFHE--------PPVWSVALPRNWQQIARWQEQEFAPPATVN 60
            |.|.|   .:.|| |||:|.:......        |||::          :|:.....|.....|
Frog    47 LTMDW---PDWAR-PRLTSAWSGPLRSGLVRSGMPPPVYN----------SRYTGYPDARNTVAN 97

  Fly    61 -KDGYKLTLDVKDY--SELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKV 122
             ...:|:.::|:.:  .||.||..| ..|.|.|..|:|:.| ||..|::|.::|.||...:|..|
Frog    98 ISQPWKVCVNVQTFKPEELTVKTKD-GFVEVSGNHEEQQKE-GGIVSKNFTKKFQLPPEVDAQTV 160

  Fly   123 TSTLSSDGVLTISVPNPP 140
            .::||.:|:|.|..|..|
Frog   161 FASLSPEGLLIIEAPVVP 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	IbpA	17..154	CDD:223149	39/135 (29%)
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	27/78 (35%)
hspb8	NP_001005658.1	alpha-crystallin-Hsps_p23-like	86..175	CDD:381838	29/90 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910