Protein Alignment Hsp22 and Hspb1

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_038588.2
• Gene: Hspb1 / 15507
• MGIID: 96240
• Length: 209
• Species: Mus musculus
• Alignment Length: 206
• Identity: 57/206 - (27%)
• Similarity: 85/206 - (41%)
• Gaps: 60/206 - (29%)

  Fly     5 PMFWRMAEEMARMPRLSSPFHAFFHEPPVWSVALPRNWQQIARW---------------QEQEFA 54
            |...|:.::...:|||          |..||     .|...|.|               .....|
Mouse    24 PAHSRLFDQAFGVPRL----------PDEWS-----QWFSAAGWPGYVRPLPAATAEGPAAVTLA 73

  Fly    55 PPA---TVNK-------------DGYKLTLDVKDYS--ELKVKVLDESVVLVEGKSEQQEAEQGG 101
            .||   .:|:             |.::::|||..::  ||.||. .|.||.:.||.|:::.|. |
Mouse    74 APAFSRALNRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKT-KEGVVEITGKHEERQDEH-G 136

  Fly   102 YSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPNPPGVQETLKEREVTI-------EQTGEP 159
            |.||.|.|::.||.|.:...|:|:||.:|.||:..|.|..|.::   .|:||       .|.|.|
Mouse   137 YISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQS---AEITIPVTFEARAQIGGP 198

  Fly   160 AKKSAEEPNDK 170
            ....:|:...|
Mouse   199 EAGKSEQSGAK 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	31/91 (34%)
Hspb1	NP_038588.2	Interaction with TGFB1I1. /evidence=ECO:0000250	74..209		44/139 (32%)
		ACD_HspB1_like	88..173	CDD:107230	31/86 (36%)