DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp22 and cryab

DIOPT Version :9

Sequence 1:	NP_001027114.1	Gene:	Hsp22 / 3772576	FlyBaseID:	FBgn0001223	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	XP_002932964.1	Gene:	cryab / 100494321	XenbaseID:	XB-GENE-971379	Length:	173	Species:	Xenopus tropicalis

Alignment Length:	142	Identity:	48/142 - (33%)
Similarity:	71/142 - (50%)	Gaps:	22/142 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SPFHAFFHEPPVWSVALPRNWQQIARWQEQEFAPPATVNKDGYKLTLDVKDYS--ELKVKVLDES 84
            |||  ||..|          :.::..|.:...: ...::||.:.:.||||.:|  ||.||||.:
Frog    44 SPF--FFRYP----------FSRLPNWIDSGLS-EMKIDKDRFSVNLDVKHFSPEELNVKVLGD- 94

  Fly    85 VVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPN-----PPGVQE 144
            .:.:.|..|:::.|. ||.||.|.||:.:|...:...:|||||.|||||:|.|.     |.....
Frog    95 FIEIHGTHEERQDEH-GYVSRDFQRRYKIPSDVDPQSITSTLSPDGVLTVSGPRKVSEVPERCIP 158

  Fly   145 TLKEREVTIEQT 156
            ..:|.:|.|..|
Frog   159 ITREEKVAISST 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	IbpA	17..154	CDD:223149	46/138 (33%)
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	35/78 (45%)
cryab	XP_002932964.1	Crystallin	1..51	CDD:366148	5/8 (63%)
cryab	XP_002932964.1	alpha-crystallin-Hsps_p23-like	65..148	CDD:381838	36/84 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010