DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fuca and fuca2

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001011291.1	Gene:	fuca2 / 496744	XenbaseID:	XB-GENE-945131	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	487	Identity:	238/487 - (48%)
Similarity:	313/487 - (64%)	Gaps:	38/487 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MPLLVALIVVWISAAEVDAQVPG-PRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPSFG 70
            :||||.|::       :.|..|| .||.|:|.|.|||.||||.|:||.|.|||:|:||:||||:|
Frog    11 LPLLVFLLL-------LQATQPGVSRTAYEPTWESLDSRPLPNWFDDVKFGIFIHWGVFSVPSYG 68

  Fly    71 SEWFWTNWKNLRNPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTSKH 135
            |||||..|:..:...||.||::||.|||.|::|..|||||.:|..:||:..::|||:||||||||
Frog    69 SEWFWWYWQGSKVASYVNFMKKNYPPDFRYEDFGPQFTAEFYNPLQWAITLEESGAKYVVLTSKH 133

  Fly   136 HDGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHLLM 200
            |:|||||.||.|:.|||:|||||||::.||..|||..::|.||||:|||||||||:..||.....
Frog   134 HEGFTLWGSKVSWNWNSVDVGPKRDLIAELVLAIRSTTNLHFGLYHSLFEWFNPLFLSDKNSSFA 198

  Fly   201 QQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRWGF 265
            .:.||:.|..||..|||.:|.|||:|||||.:||..||.|..|:|||||:||||||||||||||.
Frog   199 TRRFVDTKTLPELYELVTKYQPEILWSDGDGDAPYTYWNSTGFLAWLYNESPVRDTVVTNDRWGN 263

  Fly   266 GTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVSCN 330
            |..|.||.:|.|.||:|||.|..|||||..|:||.|||.|.:..:|:.:|.:|:::|::.||||.
Frog   264 GCICKHGGYYTCTDRYNPGHLLKHKWENCMTIDRYSWGYRRNALISEMLTIEEIVQELVETVSCG 328

  Fly   331 GNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYT-RQKEASN 394
            ||:|:|:|||..|.|..|||:||:.:|:|||.|||.||.:.||..||||:...|||| |.||.:
Frog   329 GNLLLNIGPTSDGRIPVIFEQRLKQIGQWLKLNGEAIYSTKPWRAQNDTVTAGVWYTCRPKEKA- 392

  Fly   395 GKITIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDILNEQSTEVVMLGMEDTKI 459
                :||..|.:|                       :..::..|......:.|||.:.|.| .|:
Frog   393 ----LYAIFLSWP-----------------------SKWELVLGEPKAMTEKTEVQLFGFE-KKL 429

  Fly   460 KWNADHNRLHIVFPPKNHIDKRGLDYAWTFKI 491
            .|::...:..:|..|.....:....:.|..||
Frog   430 NWSSLGEQGMVVHLPALSYSQMPAPWGWVLKI 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	219/382 (57%)
		AfuC	60..>373	CDD:226195	181/312 (58%)
		Fucosidase_C	376..492	CDD:293362	28/117 (24%)
fuca2	NP_001011291.1	Alpha_L_fucos	32..411	CDD:214829	216/406 (53%)
fuca2	NP_001011291.1	Fucosidase_C	374..461	CDD:374779	26/115 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	458	1.000	Domainoid score	I487
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119
Inparanoid	1	1.050	496	1.000	Inparanoid score	I1352
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002668
OrthoInspector	1	1.000	-	-		otm49296
Panther	1	1.100	-	-	LDO	PTHR10030
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1781
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.150