DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fuca and Fuca2

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001004218.1	Gene:	Fuca2 / 292485	RGDID:	1303053	Length:	459	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	231/459 - (50%)
Similarity:	302/459 - (65%)	Gaps:	28/459 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 YQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPSFGSEWFWTNWKNLRNPEYVQFMQRNYKPDF 98
            |.|.|.|||:||||.|:|.||.|||:|:||:|||||||||||..|:..|.|::|.||..||.|.|
  Rat    26 YDPTWESLDRRPLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQKERRPKFVDFMDNNYPPGF 90

  Fly    99 TYQEFASQFTAELFNATKWALLFKDSGARYVVLTSKHHDGFTLWPSKNSYGWNSMDVGPKRDIVK 163
            .|::|...|||:.|||.:||.|.:.|||:|||||||||:|||||.|.:|:.||::|.||||||||
  Rat    91 KYEDFGVLFTAKYFNANQWADLLQASGAKYVVLTSKHHEGFTLWGSAHSWNWNAVDEGPKRDIVK 155

  Fly   164 ELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHLLMQQHFVERKVRPEQMELVQQYLPEIIWSD 228
            ||..|:|..:||.|||||||||||:||:.:|:.....:|.|...|..||..|||.:|.||::|||
  Rat   156 ELEVAVRNRTDLHFGLYYSLFEWFHPLFLEDQSSAFQKQRFPVAKTLPELYELVTKYQPEVLWSD 220

  Fly   229 GDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRWGFGTACMHGDFYNCADRFNPGVLQAHKWEN 293
            ||..||..||.|.:|:|||||:||||||||||||||.|:.|.||.:|.|:||:|||.|..|||||
  Rat   221 GDGGAPDHYWNSTDFLAWLYNESPVRDTVVTNDRWGAGSICKHGGYYTCSDRYNPGHLLPHKWEN 285

  Fly   294 AFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVSCNGNVLINVGPTKFGTILPIFEERLRDMGR 358
            ..|:|:.|||.|.:..:.|::|.:|::|:::.||||.||:|:|:|||..|.|..|||||||.||.
  Rat   286 CMTIDKFSWGYRREAEIGDYLTIEELVKQLVETVSCGGNLLMNIGPTLDGIIPVIFEERLRQMGT 350

  Fly   359 WLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEASNGKITIYAFVLEYPYDTNELDIYPLGKDIN 423
            |||.|||.||.:..|..||||:..:||||.:.|    |..:||..|::|..         ||
  Rat   351 WLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPE----KKLVYAIFLKWPIS---------GK--- 399

  Fly   424 IFRNVMLTGIDMGTGGDILNEQSTEVVMLGMEDTKIKWNADHNRLHIVFPPKNHIDKRGLDYAWT 488
                 :..|..:|:.|:      |||.:|| ....:.|.:......:|..|:..:.:....:.||
  Rat   400 -----LFLGQPIGSLGE------TEVELLG-HGRPLTWTSSKPSGIVVELPRLSVHQMPCKWGWT 452

  Fly   489 FKIT 492
            ..:|
  Rat   453 LALT 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	215/374 (57%)
		AfuC	60..>373	CDD:226195	183/312 (59%)
		Fucosidase_C	376..492	CDD:293362	29/115 (25%)
Fuca2	NP_001004218.1	Alpha_L_fucos	23..405	CDD:214829	218/399 (55%)
		AfuC	52..>376	CDD:226195	188/323 (58%)
		Fucosidase_C	368..456	CDD:293362	29/115 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343691
Domainoid	1	1.000	453	1.000	Domainoid score	I481
eggNOG	1	0.900	-	-		E1_COG3669
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H119
Inparanoid	1	1.050	488	1.000	Inparanoid score	I1369
OMA	1	1.010	-	-		QHG62607
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002668
OrthoInspector	1	1.000	-	-		otm46213
orthoMCL	1	0.900	-	-		OOG6_102401
Panther	1	1.100	-	-	LDO	PTHR10030
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1781
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.800