DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fuca and Fuca1

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_036694.2	Gene:	Fuca1 / 24375	RGDID:	2636	Length:	462	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	223/495 - (45%)
Similarity:	311/495 - (62%)	Gaps:	47/495 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SAWMPLLVALIVVWISAAEVDAQVPGPRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPS 68
            |.|..:...|:::..::|:.....|   ..|.|:|.|||.||||:|:|:||.|:|:|:||||||:
  Rat     6 SEWWAVGFGLLLLLAASAQAGGLAP---HHYTPDWPSLDSRPLPRWFDEAKFGLFVHWGVYSVPA 67

  Fly    69 FGSEWFWTNWKNLRNPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTS 133
            :||||||.:|:..::..||:||:.||.|.|:|.:||.||||..|:..:||.||:.:||:|||||:
  Rat    68 WGSEWFWWHWQGEQSSAYVRFMKENYPPGFSYADFAPQFTARFFHPEEWADLFQAAGAKYVVLTA 132

  Fly   134 KHHDGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHL 198
            |||:|||.|||..|:.|||.||||.||:|.||.||:||. ::|:|||:||||||:||:..||.:.
  Rat   133 KHHEGFTNWPSAVSWNWNSKDVGPHRDLVGELGAAVRKR-NIRYGLYHSLFEWFHPLYLLDKKNG 196

  Fly   199 LMQQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRW 263
            |..||||..|..||..:||.:|.|::|||||:||.|..||.|.||:|||||:|||:|.||.||||
  Rat   197 LKTQHFVSTKTMPELYDLVNRYKPDLIWSDGEWECPDSYWNSTEFLAWLYNESPVKDQVVVNDRW 261

  Fly   264 GFGTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVS 328
            |...:|.||.:|||.|::.|..|..||||...::|:.|||.|.|:|:|..:...|:|:|::.|:|
  Rat   262 GQNCSCRHGGYYNCEDKYRPHSLPDHKWEMCTSVDKASWGYRRDMSMSTIVDENEIIEELVQTIS 326

  Fly   329 CNGNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEAS 393
            ..||.|:|:||.|.|.|:|||:|||..:|:||:.|||.||.|.||..|::.....||||.:..|
  Rat   327 LGGNYLLNIGPNKDGVIVPIFQERLLAVGKWLQINGEAIYASKPWRVQSEKNKTVVWYTTKDSA- 390

  Fly   394 NGKITIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDILNEQS------TEVVML 452
                 :||..|.:|.|                              .::|.||      |::.||
  Rat   391 -----VYATFLHWPED------------------------------GVVNLQSPKMTSATKITML 420

  Fly   453 GMEDTKIKWNADHNRLHIVFPPKNHIDKRGLDYAWTFKIT 492
            |||. ::.|..|.....::..|:.......::.|||.|:|
  Rat   421 GMEG-ELHWTQDPLEGVLITLPQLPPGTFPVESAWTLKLT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	201/380 (53%)
		AfuC	60..>373	CDD:226195	172/312 (55%)
		Fucosidase_C	376..492	CDD:293362	27/121 (22%)
Fuca1	NP_036694.2	Alpha_L_fucos	27..409	CDD:214829	204/421 (48%)
		AfuC	59..402	CDD:226195	185/379 (49%)
		Fucosidase_C	382..459	CDD:293362	26/113 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343690
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3669
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	488	1.000	Inparanoid score	I1369
OMA	1	1.010	-	-		QHG62607
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002668
OrthoInspector	1	1.000	-	-		otm46213
orthoMCL	1	0.900	-	-		OOG6_102401
Panther	1	1.100	-	-	O	PTHR10030
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1781
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.760