DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fuca and W03G11.3

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_510020.2	Gene:	W03G11.3 / 189173	WormBaseID:	WBGene00012225	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	482	Identity:	213/482 - (44%)
Similarity:	298/482 - (61%)	Gaps:	63/482 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVALI--VVWISAAEVDAQVPGPRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPSFGSE 72
            ::.||  ::::..|..|         |.|:|.|||.||||.||||:|.|||.|:|:||||:|.||
Worm     1 MIFLIFSILFLHLANCD---------YTPDWESLDNRPLPSWYDDSKFGIFCHWGLYSVPAFRSE 56

  Fly    73 WFWTNWKNLR-NPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTSKHH 136
            |.|..||..: :.:.|.|:.:||||..||.:||..||||.|||.::|...|.|||||.|.|||||
Worm    57 WMWWYWKGTQPDKDVVNFVDKNYKPGTTYADFAKDFTAEYFNANQFAETVKTSGARYFVFTSKHH 121

  Fly   137 DGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDD-KLHLLM 200
            :|||:|||:.|:.|||||:|||||||.||..|.:| :|:.||||:|.||||:|::.|| |.:...
Worm   122 EGFTMWPSRTSWNWNSMDIGPKRDIVGELRDAFKK-TDVHFGLYFSQFEWFHPMFLDDGKFNTTF 185

  Fly   201 QQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRWGF 265
               :.|:...|:.:::|.:|.||::||||:|:....||:::||:|||||.|||:|.||.|||||.
Worm   186 ---YPEQVSYPQMIDIVTKYNPEVVWSDGEWDKSDDYWKAKEFLAWLYNSSPVKDQVVVNDRWGT 247

  Fly   266 GTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVSCN 330
            ||...||.|...:|.::||.|...||||..|||:.|||.|.|:..|:..|:.|:|:::..|::||
Worm   248 GTMGKHGGFMTYSDHYDPGKLLEKKWENCMTLDKHSWGNRRDMKASEVNTAYEIIEQLARTIACN 312

  Fly   331 GNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEASNG 395
            ||:|:||||...|.|..|||:||.::||::....|.|:|:.|||:||||...|||||  .:.|:|
Worm   313 GNLLLNVGPNMHGQIPAIFEDRLEEIGRFVNITSEAIFGTRPWIHQNDTSASNVWYT--SKYSSG 375

  Fly   396 K------------------ITIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDIL 442
            |                  ..:||::|:..::..||      |.:...:|...|         ||
Worm   376 KKPLKNLYQNVYNFQLEEHTIVYAWILDTSHEQFEL------KSVKTTKNTTAT---------IL 425

  Fly   443 NEQSTEVVMLGMED--------TKIKW 461
               .|:||:.|.|:        :||.|
Worm   426 ---GTDVVLTGFEESDSMIILSSKIDW 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	194/400 (49%)
		AfuC	60..>373	CDD:226195	158/314 (50%)
		Fucosidase_C	376..492	CDD:293362	30/112 (27%)
W03G11.3	NP_510020.2	Alpha_L_fucos	12..377	CDD:214829	192/379 (51%)
W03G11.3	NP_510020.2	AfuC	44..>355	CDD:226195	158/314 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161241
Domainoid	1	1.000	388	1.000	Domainoid score	I418
eggNOG	1	0.900	-	-		E1_COG3669
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H119
Inparanoid	1	1.050	422	1.000	Inparanoid score	I997
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62607
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002668
OrthoInspector	1	1.000	-	-		oto18297
orthoMCL	1	0.900	-	-		OOG6_102401
Panther	1	1.100	-	-	LDO	PTHR10030
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2531
SonicParanoid	1	1.000	-	-		X1781
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790