DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fuca and AgaP_AGAP007285

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_308535.4	Gene:	AgaP_AGAP007285 / 1269881	VectorBaseID:	AGAP007285	Length:	477	Species:	Anopheles gambiae

Alignment Length:	494	Identity:	289/494 - (58%)
Similarity:	355/494 - (71%)	Gaps:	33/494 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SAWMPLLVALIVVWISAAEVDAQVPGPRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPS 68
            |.|  |..|::|..:......|      .:|:|.|.|||.||||:||||||||||:|:|||:|||
Mosquito     7 SVW--LCCAVVVFGVLCLGCTA------GKYEPTWESLDSRPLPKWYDDAKVGIFIHWGVYAVPS 63

  Fly    69 FGSEWFWTNWKNLRNPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTS 133
            :||||||.||:..|..||||||..||||.||||:|||.|||||||||:||.||..||||||||||
Mosquito    64 YGSEWFWINWQGSRTEEYVQFMANNYKPGFTYQDFASDFTAELFNATEWAELFARSGARYVVLTS 128

  Fly   134 KHHDGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHL 198
            |||:|:||||||:::|||:|||||.||::.|||.|:|....|.||:|||||||||.|:.:||||:
Mosquito   129 KHHEGYTLWPSKHTFGWNAMDVGPHRDVLGELANAVRATGQLTFGVYYSLFEWFNRLYLNDKLHV 193

  Fly   199 LMQQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRW 263
            .||:.:|:.||.||..||:..|.||::|||||||||..||:::||.||||||||||||:||||||
Mosquito   194 FMQREYVDGKVWPELQELINTYRPEVLWSDGDWEAPDGYWKAKEFFAWLYNDSPVRDTIVTNDRW 258

  Fly   264 GFGTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVS 328
            |.||.|:||||:.|:||:||||||.||||||.|:||.|||.|.:..|.||||:.|:|.|::||||
Mosquito   259 GMGTLCLHGDFHTCSDRYNPGVLQKHKWENAMTIDRKSWGHRVNARLEDFMTTDELIGELVTTVS 323

  Fly   329 CNGNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEAS 393
            |.||:||||||||.|||..||.|||.:||||||.||..||.|.||.|||||:.|:||||..|.:|
Mosquito   324 CGGNILINVGPTKAGTIEAIFAERLVEMGRWLKVNGPAIYKSQPWEYQNDTLTGSVWYTATKGSS 388

  Fly   394 NGKI---TIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDILNEQSTEVVMLGME 455
            |.:.   ||:|.||:|||.||.:   .||...|...|:                  .::.|||.
Mosquito   389 NRRSNFRTIFATVLDYPYKTNSV---RLGAFSNQVTNI------------------AQITMLGY- 431

  Fly   456 DTKIKWNADHNRLHIVFPPKNHIDKRGLDYAWTFKITIT 494
            :|.:||....:.:.:.|||||.||:..|.:|||.|||:|
Mosquito   432 NTALKWKPTDDGIMVEFPPKNEIDRLELKHAWTLKITLT 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	255/383 (67%)
		AfuC	60..>373	CDD:226195	213/312 (68%)
		Fucosidase_C	376..492	CDD:293362	44/118 (37%)
AgaP_AGAP007285	XP_308535.4	Alpha_L_fucos	23..416	CDD:214829	261/401 (65%)
		AfuC	55..449	CDD:226195	248/415 (60%)
		Fucosidase_C	371..468	CDD:293362	44/118 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	529	1.000	Domainoid score	I1028
eggNOG	1	0.900	-	-		E1_COG3669
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H119
Inparanoid	1	1.050	614	1.000	Inparanoid score	I2329
OMA	1	1.010	-	-		QHG62607
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002668
OrthoInspector	1	1.000	-	-		oto110768
Panther	1	1.100	-	-	LDO	PTHR10030
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1781
TreeFam	1	0.960	-	-
	12	11.930