DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fuca and plxnb3

DIOPT Version :9

Sequence 1:	NP_001303363.1	Gene:	Fuca / 3772574	FlyBaseID:	FBgn0285958	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_002935540.2	Gene:	plxnb3 / 100490083	XenbaseID:	XB-GENE-856492	Length:	1925	Species:	Xenopus tropicalis

Alignment Length:	130	Identity:	29/130 - (22%)
Similarity:	48/130 - (36%)	Gaps:	47/130 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 ASN----GKITIYAFVLE-------YPYDTNEL-DIYPL------GKDINIFRNVMLTG----ID 434
            |||    |.:.:|...|:       :.|....| .::||      |..|.|..:.:|||    |.
Frog   934 ASNAEESGPVEVYVDALQPGVSVEHFTYQDPVLQSLHPLQGPIAGGTLITITGSKLLTGDLINIT 998

  Fly   435 MG-------------------TGGDILNEQSTEVVMLG-----MEDTKIKWNADHNRLHIVFPPK 475
            :|                   ||...:.|:....|..|     :||||..: .::..:.:|:|.:
Frog   999 VGDIPCKIPNGGVAEGEIHCVTGASSVLEELPVSVFYGSAKRILEDTKYSY-TENPTISLVYPSR 1062

Fly 476 475
Frog 1063 1062

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fuca	NP_001303363.1	Alpha_L_fucos	28..409	CDD:214829	6/27 (22%)
		AfuC	60..>373	CDD:226195
		Fucosidase_C	376..492	CDD:293362	29/130 (22%)
plxnb3	XP_002935540.2	Sema_plexin_B3	81..513	CDD:200538
		PSI	515..563	CDD:366642
		TIG_plexin	574..660	CDD:375449
		PSI	674..>703	CDD:366642
		TIG_2	726..825	CDD:375492
		IPT	874..963	CDD:387656	7/28 (25%)
		IPT	964..1051	CDD:387656	20/87 (23%)
		IPT	1053..1173	CDD:387656	2/10 (20%)
		Plexin_cytopl	1356..1891	CDD:369821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165168992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930