DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32269 and Klkb1

DIOPT Version :9

Sequence 1:	NP_001261363.1	Gene:	CG32269 / 3772569	FlyBaseID:	FBgn0052269	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	105/344 - (30%)
Similarity:	158/344 - (45%)	Gaps:	59/344 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ISGNKSRGKVIAKTVHSDMLWRCEYLILGMLLLAELTQLGEAVTANQQRRNRRLRSDNGTKRLTG 69
            :.|..:..:...||:      ||::....:        |.:...|...:.:.||.:|....|:|
  Rat   312 VQGADACQETCTKTI------RCQFFTYSL--------LPQDCKAEGCKCSLRLSTDGSPTRIT- 361

  Fly    70 TKNQTGIRSNRRQGTA-RKLSAKRVNQNKKAATSSKIQSRIVGGTSTTISTTPYIVQLR----RG 129
                     ...||:: ..|...:|.::....|  ||.:||||||::::...|:.|.|:    ..
  Rat   362 ---------YEAQGSSGYSLRLCKVVESSDCTT--KINARIVGGTNSSLGEWPWQVSLQVKLVSQ 415

  Fly   130 SNLCSGSLITEQWVLTAAHCVKGYSASD-FTVRGGTTTLDGSDGVT--RSVSSIHVAPKFTSKKM 191
            :::|.||:|..||:||||||..|....| :.:.||...|......|  .|:..:.:..|:...:.
  Rat   416 NHMCGGSIIGRQWILTAAHCFDGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEG 480

  Fly   192 NMDAALLKLNQSLTGTNIGTISMGNYRP-----KAGSRV-----RIAGWGVTKEGSTTASKTLQT 246
            :.|.||:||...|..|..       .:|     ||.:..     .:.|||.|||...| ...||.
  Rat   481 SYDIALIKLQTPLNYTEF-------QKPICLPSKADTNTIYTNCWVTGWGYTKERGET-QNILQK 537

  Fly   247 AQIRVVRQQKCRKDYRGQATITKYMLCA--RAAGKDSCSGDSGGPVTRNNT----LLGIVSFGYG 305
            |.|.:|..::|:|.|| ...|||.|:||  :..|.|:|.||||||:...::    |:||.|:|.|
  Rat   538 ATIPLVPNEECQKKYR-DYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEG 601

  Fly   306 CARAGYPGVYTAVVAIRQW 324
            |||...|||||.|.....|
  Rat   602 CARKEQPGVYTKVAEYIDW 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32269	NP_001261363.1	Tryp_SPc	108..324	CDD:214473	85/238 (36%)
CG32269	NP_001261363.1	Tryp_SPc	121..324	CDD:238113	79/225 (35%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	15/86 (17%)
		Tryp_SPc	390..621	CDD:214473	86/240 (36%)
		Tryp_SPc	391..621	CDD:238113	85/239 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910