DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11714 and btbd3b

DIOPT Version :9

Sequence 1:	NP_001027123.1	Gene:	CG11714 / 3772566	FlyBaseID:	FBgn0036170	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_003199784.1	Gene:	btbd3b / 562593	ZFINID:	ZDB-GENE-041210-282	Length:	517	Species:	Danio rerio

Alignment Length:	315	Identity:	77/315 - (24%)
Similarity:	123/315 - (39%)	Gaps:	70/315 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DCTFIIEDESGGSQSFPCHKLLFSCASDVFDRMLYGDYIESTSGVVRLNDVQPDIFEKFRDYVYG 93
            |..|:: .:|||:|..|.||.:.:..|.||..|.||:..|.|. .:|:.||:|..|.....|:|
Zfish   116 DVHFVV-GQSGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDTD-EIRIPDVEPPAFLAMLKYIY- 177

  Fly    94 YECDKLQKYDFDTLIRLCEFANKYLVQSLEEDCVKDL---LIRKNTFDMGELLRLFQCAHRMNRK 155
              ||::. ...||::.....|.||:|..|...||..|   |..||.           |.
Zfish   178 --CDEID-LSADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNA-----------CI------ 222

  Fly   156 SLINQIAWELKCTFKSTLDHSGVYEFNCEVFKHYIEVIASKISEADRFRLLEMYLKYNGIEELES 220
             |::|     .|.|:..           ::.:...|||.::         .|:.||.:|..:
Zfish   223 -LLSQ-----SCLFEEP-----------DLTQRCWEVIDAQ---------AELALKSDGFCD--- 258

  Fly   221 AGQVDSQDATEANTTTITTTNEVENQESELPSTSCVPLKTECSFAVPNKKASFVSDLLALIDFGK 285
               :|||..............|:...|:.|........:.|.:.::.||: ..:...:.||....
Zfish   259 ---IDSQTLESILRRETLNAKEIVVFEAALSWADAECQRREMNTSIDNKR-KVLGQSIYLIRIPT 319

  Fly   286 LSPKEFYDGPGKSNFLSLAEKYEHM--YQIAKNCVTAKDELQL----KMALTTEQ 334
            :...:|.:|..:|..|:|.|..:..  |..||     |.|||.    :..||.::
Zfish   320 MGLDDFANGAAQSGVLTLNETNDIFLWYTAAK-----KPELQFASQPRKGLTPQK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11714	NP_001027123.1	BTB	27..131	CDD:279045	36/104 (35%)
CG11714	NP_001027123.1	BTB	29..133	CDD:197585	37/106 (35%)
btbd3b	XP_003199784.1	BTB	108..211	CDD:279045	35/100 (35%)
		BTB	116..215	CDD:197585	36/104 (35%)
		BACK	221..327	CDD:197943	24/144 (17%)
		PHR	372..515	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810