Protein Alignment CG11714 and BTBD2

DIOPT Version :10

• Sequence 1: NP_001027123.1
• Gene: CG11714 / 3772566
• FlyBaseID: FBgn0036170
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: XP_047295021.1
• Gene: BTBD2 / 55643
• HGNCID: 15504
• Length: 585
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 66/311 - (21%)
• Similarity: 107/311 - (34%)
• Gaps: 92/311 - (29%)

  Fly    41 SQSFPCHKLLFSCASDVFDRMLYGDYIESTSGVVRLNDVQPDIFEKFRDYVYGYECDKLQKYDFD 105
            ||..|.|:.:.:..|.|||.|..|. :.:||..:.|.||:|..|.....::|.   |::| ...:
Human   129 SQRIPAHRFVLAVGSAVFDAMFNGG-MATTSTEIELPDVEPAAFLALLKFLYS---DEVQ-IGPE 188

  Fly   106 TLIRLCEFANKYLVQSLEEDCVKDL---LIRKNTF-----------DMGEL------LRLFQC-- 148
            |::.....|.||.|.:||..||:.|   |...|.|           |:..|      .:.|.|
Human   189 TVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQAGVQWHDLSSLQPPPPAFKRFSCLS 253

  Fly   149 --------------AHRMNRKSLINQIAWEL-KCTFK------------STLDHSGVYEFNCEVF 186
                          |.:..:|......:..| ||..:            ..:|.:.......|.|
Human   254 LHSSWDYRPPPPRLAKKKEKKKPERTFSLSLRKCQARLFDEPQLASLCLENIDKNTADAITAEGF 318

  Fly   187 KHY-IEVIASKISEADRFRLLEMYLKYNGIEELESAGQVDSQDATEANTTTITTTNEVENQESEL 250
            ... ::.:.: :.|.|...:.|:.| :|                      .:...:|.|.|..:|
Human   319 TDIDLDTLVA-VLERDTLGIREVRL-FN----------------------AVVRWSEAECQRQQL 359

  Fly   251 PSTSCVPLKTECSFAVPNKKASFVSDLLALIDFGKLSPKEFYDGPGKSNFL 301
            ..|             |..:...:...|.||.|..::.:||..||.:|..|
Human   360 QVT-------------PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGIL 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11714	NP_001027123.1	BTB_POZ_ZBTB_KLHL-like	27..117	CDD:349497	22/75 (29%)
BTBD2	XP_047295021.1	BTB_POZ_BTBD1_2	95..221	CDD:349590	31/96 (32%)
		BACK	288..382	CDD:475122	18/130 (14%)
		PHR	435..584	CDD:462339