DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11714 and btbd6b

DIOPT Version :9

Sequence 1:	NP_001027123.1	Gene:	CG11714 / 3772566	FlyBaseID:	FBgn0036170	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_005160551.1	Gene:	btbd6b / 553533	ZFINID:	ZDB-GENE-030829-65	Length:	535	Species:	Danio rerio

Alignment Length:	334	Identity:	81/334 - (24%)
Similarity:	130/334 - (38%)	Gaps:	68/334 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TLPNSKMRSCMM---ELGRTNRHTDCTFIIEDESGGSQSFPCHKLLFSCASDVFDRMLYGDYIES 69
            |.|..:.|:.:|   ||     ..|..|:: ...|.||..|.||.:.:..|.||..|.|||..|.
Zfish   115 THPTLRERNALMFNNEL-----MADVHFVV-GPPGASQKVPAHKYVLAVGSSVFGAMFYGDLAEG 173

  Fly    70 TSGVVRLNDVQPDIFEKFRDYVYGYECDKLQKYDFDTLIRLCEFANKYLVQSLEEDCVKDL---L 131
            .| .:.:.||:|..|.....|:|..|.:    .:.||::.....|.||:|.:|.:.||..|   |
Zfish   174 ES-EIHIPDVEPAAFLILLKYMYSDEIE----LEADTVLATLYAAKKYIVPALAKACVTFLETSL 233

  Fly   132 IRKNTFDMGELLRLFQCAHRMNRKSLINQIAWELKCTFKSTLDHSGVYEFNCEVFKHYIEVIASK 196
            ..||...:....|||:       :..:....||:.........||   |..||:....:|:|..:
Zfish   234 EAKNACVLLSQSRLFE-------EPELTLRCWEVIDAQAELALHS---EGFCEIDLQTLEIILKR 288

  Fly   197 ISEADRFRLLEMYLKYNGIEELESAGQVDSQDATEANTTTITTTNEVENQESELPSTSCVPLKTE 261
                               |.|.:...|..|.|.:...        .|.:...|..|:
Zfish   289 -------------------ETLNTREAVVFQAALDWAV--------AECKRQGLGPTA------- 319

  Fly   262 CSFAVPNKKASFVSDLLALIDFGKLSPKEFYDGPGKSNFLSLAEKYE-HMYQIAKNCVTAKDELQ 325
                 .||:| .:...|.|:....::.:||.:|..:|:.|:|.|.:: .::..|.|....:..||
Zfish   320 -----RNKRA-VLGKALYLVRIPTMTLEEFANGAAQSDVLTLEETHDVFLWYTAANKPKLEFPLQ 378

  Fly   326 LKMALTTEQ 334
            .:..||.::
Zfish   379 KRKGLTPQR 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11714	NP_001027123.1	BTB	27..131	CDD:279045	34/106 (32%)
CG11714	NP_001027123.1	BTB	29..133	CDD:197585	35/106 (33%)
btbd6b	XP_005160551.1	BTB	126..229	CDD:279045	36/113 (32%)
		BTB	134..233	CDD:197585	34/104 (33%)
		BACK	239..345	CDD:197943	27/155 (17%)
		PHR	390..533	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810