DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11714 and BTBD17

DIOPT Version :9

Sequence 1:	NP_001027123.1	Gene:	CG11714 / 3772566	FlyBaseID:	FBgn0036170	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_011523093.1	Gene:	BTBD17 / 388419	HGNCID:	33758	Length:	479	Species:	Homo sapiens

Alignment Length:	164	Identity:	41/164 - (25%)
Similarity:	64/164 - (39%)	Gaps:	22/164 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 MMELGRTNRHTDCTFIIEDESGGSQS---FPCHKLLFSCASDVFDRMLYGDYIESTSGVVRLNDV 79
            :.||.|....:|  .::..::.|:..   |..|:||....|::|..:|      |......|.:.
Human    54 LQELLRQGNASD--VVLRVQAAGTDEVRVFHAHRLLLGLHSELFLELL------SNQSEAVLQEP 110

  Fly    80 Q--PDIFEKFRDYVYGYECDKLQKYDFDTLIRLCEFANKYLVQSLEEDCVKDLLIRKNTFDMGEL 142
            |  ..:|:||..|:|   |.:|... ....|.|...|.||.|.||:.. |.|.:........|..
Human   111 QDCAAVFDKFIRYLY---CGELTVL-LTQAIPLHRLATKYGVSSLQRG-VADYMRAHLAGGAGPA 170

  Fly   143 LRLFQCA----HRMNRKSLINQIAWELKCTFKST 172
            :..:..|    ....|:|.:..:||.|.....||
Human   171 VGWYHYAVGTGDEALRESCLQFLAWNLSAVAAST 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11714	NP_001027123.1	BTB	27..131	CDD:279045	29/108 (27%)
CG11714	NP_001027123.1	BTB	29..133	CDD:197585	29/108 (27%)
BTBD17	XP_011523093.1	BTB	54..159	CDD:279045	32/117 (27%)
		BTB	65..163	CDD:197585	29/110 (26%)
		BACK	170..268	CDD:197943	8/35 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900